Evidence map›Paper›PMID 37887139›Full record

ArticleBiosensors2023

Intensity Interrogation-Based High-Sensitivity Surface Plasmon Resonance Imaging Biosensor for Apoptosis Detection in Cancer.

Xin Yuan, Zhenxiao Niu, Lang Liu, Youjun Zeng, Lin Ma, Zhaogang Nie, Zhen Tian, Dongyun Kai, Fangteng Zhang, Guanyu Liu and 2 more

Abstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xin YuanSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China.
Zhenxiao NiuSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Lang LiuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China.
Youjun ZengSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.ORCID 0000-0002-5559-2977
Lin MaSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Zhaogang NieSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Zhen TianSchool of Physical Science and Information Technology, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0001-5518-3105
Dongyun KaiSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Fangteng ZhangSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Guanyu LiuSchool of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Siwei LiSchool of Mechano-Electronic Engineering, Zhuhai City Polytechnic, Zhuhai 519000, China.
Zhengqiang YuanSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China.ORCID 0000-0003-1059-9400

Funding

Guangdong University of Technology Guangdong Natural Science Foundation and Province Project (2023A1515011708)Guangdong University of Technology Guangzhou Science and Technology Plan Project (2023A04J1711)Guangdong University of Technology National Natural Science Foundation of China (grant number 82173850)Zhuhai City Polytechnic Guangdong regular universities characteristic innovation projects (Grant No. 2022KTSCX314)
6 · The paper itself

Abstract

Intensity interrogation-based surface plasmon resonance imaging (ISPRi) sensing has a simple schematic design and is the most widely used surface plasmon resonance technology at present. In this study, we report the successful development of a novel high-sensitivity ISPRi biosensor and its application for apoptosis detection in cancer cells. By optimizing the excitation wavelength and excitation angle, we achieved a refractive index resolution (RIR) of 5.20 × 10

Indexed as

Biosensing TechniquesNeoplasmsApoptosisHumansRefractometrySurface Plasmon Resonanceapoptosiscancercaspase-3SPRitherapeutic efficacy assessment

Identifiers

PMID37887139
PMCPMC10605221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.