Evidence map›Paper›PMID 37887129›Full record

ArticleBiosensors2023

Ruthenium-Anchored Carbon Sphere-Customized Sensor for the Selective Amperometric Detection of Melatonin.

Sivaguru Jayaraman, Thenmozhi Rajarathinam, Hyeon-Geun Jang, Dinakaran Thirumalai, Jaewon Lee, Hyun-Jong Paik, Seung-Cheol Chang

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Preparation of CHS-FeMikrochimica acta · 2025
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sivaguru JayaramanDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.
Thenmozhi RajarathinamDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-3597-5225
Hyeon-Geun JangDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0009-0008-7030-2350
Dinakaran ThirumalaiBIT Convergence-Based Innovative Drug Development Targeting Metainflammation, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-9005-5990
Jaewon LeeBIT Convergence-Based Innovative Drug Development Targeting Metainflammation, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0003-3203-2130
Hyun-Jong PaikDepartment of Polymer Science and Engineering, Pusan National University, Busan 46241, Republic of Korea.
Seung-Cheol ChangDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.
Pusan National University · KR

Funding

Korea Institute for Advancement of Technology P0008763Korea Institute for Advancement of Technology P0022108National Research Foundation of Korea 2022R1I1A3072535Pusan National University Specialization Project
6 · The paper itself

Abstract

Melatonin (MT), a pineal gland hormone, regulates the sleep/wake cycle and is a potential biomarker for neurodegenerative disorders, depression, hypertension, and several cancers, including prostate cancer and hepatocarcinoma. The amperometric detection of MT was achieved using a sensor customized with ruthenium-incorporated carbon spheres (Ru-CS), possessing C- and O-rich catalytically active Ru surfaces. The non-covalent interactions and ion-molecule adducts between Ru and CS favor the formation of heterojunctions at the sensor-analyte interface, thus accelerating the reactions towards MT. The Ru-CS/Screen-printed carbon electrode (SPCE) sensor demonstrated the outstanding electrocatalytic oxidation of MT owing to its high surface area and heterogeneous rate constants and afforded a lower detection limit (0.27 μM), high sensitivity (0.85 μA μM

Indexed as

MelatoninRutheniumCarbonElectrochemical TechniquesElectrodesEpinephrineOxidation-ReductionCarbonEpinephrineMelatoninRutheniumamperometric sensorcarbon sphereslower detection limitmelatoninpharmaceutical samplesruthenium

Identifiers

PMID37887129
PMCPMC10605478
OpenAlexW4387744870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.