Evidence map›Paper›PMID 37886726›Full record

ArticleInternational journal of nursing and health care research2023

Uncovering Novel Biomarkers of Inflammation as Potential Screening Targets of Disease Risk in Healthcare Shift Workers: A Pilot Study.

Aisha Q Atwater, Oscar Castanon-Cervantes

Open access · hybridAbstract read
In one paragraph

Article in International journal of nursing and health care research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Impaired Responses to In Vitro Lipopolysaccharide-Induced Stimulation After Long-Term, Rotating Shift Work.International journal of environmental research and public health · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aisha Q AtwaterDepartment of Neurobiology and Neuroscience Institute, Morehouse School of Medicine; Atlanta, GA. USA.
Oscar Castanon-CervantesDepartment of Neurobiology and Neuroscience Institute, Morehouse School of Medicine; Atlanta, GA. USA.
Morehouse School of Medicine · US

Funding

Renewal Application for Clinical Research Education and Career Development (CRECDR25MD007589 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI PRISCILLA E PEMU, Alexander Quarshie · 2012 to 2026
$5.4M
Assessment of Inflammatory Responses and Novel Systemic Signals as Potential Screening Targets of Shift-Work Related Disruption.SC1GM144022 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI CASTANON-CERVANTES, OSCAR · 2022 to 2025
$1.4M
UNCOVERING BIOLOGICAL MARKERS OF DISEASE RISK IN SHIFT WORKERSSC2GM125493 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI CASTANON-CERVANTES, OSCAR · 2018 to 2020
$426k
NIGMS NIH HHS SC1 GM144022NIGMS NIH HHS SC2 GM125493NIMHD NIH HHS R25 MD007589
6 · The paper itself

Abstract

Shift work, experienced by nearly 30% of the U.S. workforce, is hazardous to health and has become a pervasive labor practice in the healthcare sector worldwide. It increases the risk of stroke, diabetes, cancer, and cardiovascular disease. Nonetheless, specific screening targets for shift workers still need to be defined. In this study, we have begun uncovering these targets as specific low-grade systemic inflammation markers and functional endotoxin-elicited responses that may foreshadow disease risk in shift workers. One hundred four participants (normothermic and normotensive) were healthy, non-smoking, and drug- and medication-free volunteers recruited from Atlanta area hospitals and medical schools. We assessed the concentration of three proteins in plasma samples from day workers and shift workers (lipopolysaccharide-binding protein, IL-10, and TNF-α), and the relationship between these baseline biomarkers and their response to an

Indexed as

ex-vivo endotoxin challengeInflammatory responseLow-grade systemic inflammationLPSShift workSystemic endotoxemia

Identifiers

PMID37886726
PMCPMC10601993
OpenAlexW4386544619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.