Evidence map›Paper›PMID 37886535›Full record

ArticleResearch square2023

Welcome to the next generation of Malaria Rapid Diagnostic Tests: Comparative Analysis of NxTek Eliminate Malaria P.f, Biocredit Malaria Ag Pf, and SD Bioline Malaria Ag Pf for Plasmodium falciparum Diagnosis in Ghana.

Tolulope A Kayode, Agyapong Kofi Addo Addo, Thomas Kwame Addison, Austine Tweneboah, Stephen Opoku Afriyie, Dawood Ackom Abass, Ayesha Seth, Abraham K Badu-Tawiah, Kingsley Badu, Cristian Koepfli

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Tolulope A KayodeUniversity of Notre Dame.
Agyapong Kofi Addo AddoKwame Nkrumah University of Science and Technology.
Thomas Kwame AddisonKwame Nkrumah University of Science and Technology.
Austine TweneboahKwame Nkrumah University of Science and Technology.
Stephen Opoku AfriyieKwame Nkrumah University of Science and Technology.
Dawood Ackom AbassKwame Nkrumah University of Science and Technology.
Ayesha SethThe Ohio State University.
Abraham K Badu-TawiahThe Ohio State University.
Kingsley BaduKwame Nkrumah University of Science and Technology.
Cristian KoepfliUniversity of Notre Dame.
Kwame Nkrumah University of Science and Technology · GHThe Ohio State University · USUniversity of Notre Dame · US

Funding

Malaria Management through an On-demand Diagnostic Approach using Novel Ionic ProbesR01AI143809 · NIAID · OHIO STATE UNIVERSITY · PI BADU-TAWIAH, ABRAHAM · 2019 to 2023
$1.3M
NIAID NIH HHS R01 AI143809
6 · The paper itself

Abstract

Background: Accurate diagnosis and timely treatment are crucial in combating malaria. Methods: We evaluated the diagnostic performance of three Rapid Diagnostic Tests (RDTs) in diagnosing febrile patients, namely: Abbott NxTek Eliminate Malaria Ag Pf (detecting HRP2), Rapigen Biocredit Malaria Ag Pf (detecting HRP2 and LDH on separate bands), and SD Bioline Malaria Ag Pf (detecting HRP2). Results were compared to qPCR. Results: Among 449 clinical patients, 45.7% (205/449) tested positive by qPCR for Conclusion: The Biocredit and NxTek RDTs demonstrated comparable diagnostic efficacies and both RDTs performed better than Bioline RDT.

Indexed as

HRP2LDHMalaria diagnosisrapid diagnostic testultrasensitive RDT

Identifiers

PMID37886535
PMCPMC10602185
OpenAlexW4387770742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.