Evidence map›Paper›PMID 37886500›Full record

ArticleResearch square2023

Higher cadmium exposure was associated with sex-specific thyroid dysfunction: Consistent evidence from two independent cross-sectional studies based on urinary and blood cadmium measurements.

Ranqi Shao, Liqin Su, Peng Wang, Xu Han, Ting Wang, Jun Dai, Yi Gu, Jiao Luo, Lifang Deng, Jingping Liu

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ranqi ShaoNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention.
Liqin SuNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention.
Peng WangNanjing Agricultural University.
Xu HanNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention.
Ting WangNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention.
Jun DaiNanjing Agricultural University.
Yi GuNanjing Agricultural University.
Jiao LuoNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention.
Lifang DengYuhu Center for Disease Control and Prevention.
Jingping LiuChangde Center for Disease Control and Prevention.
Nanjing Agricultural University · CNTaiwan Centers for Disease Control · TW

Funding

Selenium, other risk factors and cognitive decline in rural elderly ChineseR01AG019181 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GAO, SUJUAN · 2003 to 2014
$4.1M
NIA NIH HHS R01 AG019181
6 · The paper itself

Abstract

Population-based studies on the association between cadmium (Cd) exposure and thyroid function are limited and have shown conflicting results. Two independent cross-sectional studies using different Cd biomarkers were carried out in six rural areas with different soil Cd levels in China. Thyroid dysfunction was defined based on levels of thyroid stimulating hormone (TSH) and free thyroxine (FT4). Both multivariable linear regression, multiple logistic regression and restrictive cubic splines models were used to estimate the association between Cd and thyroid dysfunction. For both of the two independent studies, higher Cd levels were observed to be associated with lower TSH levels and higher risk of thyroid dysfunction. The negative relationship between urinary Cd and TSH was found in both total participants (β = -0.072,

Indexed as

CadmiumHealth risk assessmentThyroid dysfunctionThyroid hormone

Identifiers

PMID37886500
PMCPMC10602156
OpenAlexW4387772056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.