ArticleResearch square2023
A Scan of Pleiotropic Immune Mediated Disease Genes Identifies Novel Determinants of Baseline FVIII Inhibitor Status in Hemophilia-A.
Tom Howard, Marcio Almieda, Vincent Diego, Kevin Viel, Bernadette Luu, Karin Haack, Rajalingam Raja, Afshin Ameri, Meera Chitlur, Natalia Rydz and 23 more
Open access · greenAbstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
33 authors at 1 institution in 1 country.
Tom HowardUniversity of Texas Rio Grande Valley School of Medicine.
Marcio Almieda
Vincent Diego
Kevin Viel
Bernadette Luu
Karin Haack
Rajalingam RajaUniversity of California, San Francisco.
Afshin Ameri
Meera Chitlur
Natalia Rydz
David Lillicrap
Raymond Watts
Craig Kessler
Christopher Ramsey
Long Dinh
Benjamin Kim
Jerry Powell
Juan Peralta
Ruayda Bouls
Shirley Abraham
Yu-Min Shen
Carlos Murillo
Henry Mead
Paul Lehmann
Eli Fine
Miguel Escobar
Satish Kumar
Sarah Williams-Blangero
Carol Kasper
Laura Almasy
Shelley Cole
John Blangero
Barbara Konkle
University of California, San Francisco · US
Funding
Workforce Development CoreU54HG013247 · NHGRI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI John Blangero · 2023 to 2026
$10.5MMechanisms of Race-Based Differences in Factor VIII Immunogenicity in HemophiliaRC2HL101851 · NHLBI · SEPULVEDA RESEARCH CORPORATION · PI HOWARD, TOM EUGENE, PRATT, KATHLEEN PALMER · 2009 to 2010
$6.5MConstruction of a Biomedical Research Facility at the U*C06RR020547 · NCRR · UNIV/TEXAS BROWNSVILLE & SOUTHMOST COLL · PI KROUSE, JOHN H · 2010 to 2010
$4.0MGenetic Variation in Factor IX and Thrombosis RiskR01HL072533 · NHLBI · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI HOWARD, TOM E. · 2003 to 2006
$1.5MGenetic Variation in Factor IX and Thrombosis RiskK08HL071130 · NHLBI · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI HOWARD, TOM E. · 2002 to 2006
$634kNCRR NIH HHS C06 RR020547NHGRI NIH HHS U54 HG013247NHLBI NIH HHS K08 HL071130NHLBI NIH HHS R01 HL072533NHLBI NIH HHS RC2 HL101851
6 · The paper itselfAbstract
Hemophilia-A (HA) is caused by heterogeneous loss-of-function factor (F)VIII gene (
Indexed as
Autoimmune-/autoinflammatory-disordersCandidate geneFactor VIIIFactor VIII gene (F8) mutationsFactor VIII inhibitorsGene-centric association scanHemophilia AImmune-mediated disease genes and gene variantsImmune-mediated diseasesPleiotropicRace/ethnicity
Identifiers
PMID37886476
PMCPMC10602130
OpenAlexW4387736730
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390