Evidence map›Paper›PMID 37886369›Full record

ArticleJournal of immunology research2023

Irradiation Attenuates Systemic Lupus Erythematosus-Like Morbidity in NZBWF1 Mice: Focusing on CD180-Negative Cells.

Kazuko Fujita, Taku Kuwabara, Bing Wang, Kaoru Tanaka, Kei Ito, Yuri Akishima-Fukasawa, Tetuo Mikami, Yoshikiyo Akasaka, Toshiharu Ishii

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kazuko FujitaDepartment of Pathology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.ORCID https://orcid.org/0000-0001-6297-8475
Taku KuwabaraDepartment of Molecular Immunology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.
Bing WangInstitute for Radiological Science, National Institutes for Quantum Science and Technology, Chiba-City, Chiba 263-8555, Japan.ORCID https://orcid.org/0000-0002-7180-639X
Kaoru TanakaInstitute for Radiological Science, National Institutes for Quantum Science and Technology, Chiba-City, Chiba 263-8555, Japan.
Kei ItoDepartment of Pathology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.
Yuri Akishima-FukasawaDepartment of Pathology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.
Tetuo MikamiDepartment of Pathology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.
Yoshikiyo AkasakaDepartment of Pathology, School of Medicine, Toho University, Ota-Ku, Tokyo 143-8540, Japan.
Toshiharu IshiiDepartment of Pathology, Saiseikai Yokohamashi Tobu Hospital, Kanagawa, Yokohama-City 230-8765, Japan.
Toho University · JPNational Institutes for Quantum Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies that can induce systemic inflammation. Ultraviolet-A and X-ray irradiation have been reported to have therapeutic effects in patients with SLE. We previously demonstrated that CD180-negative cells, these are radiosensitive, contribute to the development of SLE-like morbidity in NZBWF1 mice. In this study, the effects of irradiation on SLE-like morbidity manifestations in NZBWF1 mice and on CD180-negative cells were investigated. Whole-body irradiation, excluding the head, attenuated SLE-like morbidity

Indexed as

Lupus Erythematosus, SystemicAnimalsAntigens, CDAutoantibodiesB-LymphocytesHumansKidneyMiceWhole-Body IrradiationAntigens, CDAutoantibodiesCD180 protein, human

Identifiers

PMID37886369
PMCPMC10599955
OpenAlexW4387736429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.