ArticleChemical science2023
Programmable synthesis of difluorinated hydrocarbons from alkenes through a photocatalytic linchpin strategy.
Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A sulfinate-azide hybrid reagent for sequential radical fluoroalkylation and click reaction.Chemical science · 2026Article
- Unified Synthesis of Unconventional α-Polyhalogenated Amines Through Hydroaminoalkylation.Angewandte Chemie (International ed. in English) · 2026Article
- Carbocycle editing of ketones proceeds via a radical-mediated bidirectional C-C bond cleavage/coupling strategy.Nature communications · 2026Article
- Fe-LMCT Photodecarboxylation for (Hetero)arene Chloro- and Bromodifluoromethylation: Rapid Access to Aromatic Acyl Fluorides.Organic letters · 2026Article
- A practical photocatalytic strategy for radical (deuterio)difluoromethylation using imidazolium reagents.Chemical science · 2025Article
- Modular synthesis of CFNature communications · 2025Article
- Radical Replacement Process for Ligated Boryl Radical-Mediated Activation of Unactivated Alkyl Chlorides for C(spJournal of the American Chemical Society · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of difluoromethylene moieties into organic molecules has garnered significant attention due to their profound influence on the physicochemical and biological properties of compounds. Nonetheless, the existing approaches for accessing difluoroalkanes from readily available feedstock chemicals remain limited. In this study, we present an efficient and modular protocol for the synthesis of difluorinated compounds from alkenes, employing the readily accessible reagent, ClCF
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Registered trials
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