ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Neighborhood greenspace and neighborhood income associated with white matter grade worsening: Cardiovascular Health Study.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Green Environments for Sustainable Brains: Parameters Shaping Adaptive Neuroplasticity and Lifespan Neurosustainability-A Systematic Review and Future Directions.International journal of environmental research and public health · 2025Pooled it
- Neighborhood greenspace and brain imaging outcomes in older adults without dementia from three US Alzheimer's Disease Research Centers.Health & place · 2026Article
- Urban greenspace and dementia: Measures, mechanisms, and methodological guidance.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Mixtures of key components of the external exposome in association with MRI biomarkers of brain structure: Multi-Ethnic Study of Atherosclerosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- From cradle to cortex: An exposome- and equity-centered perspective of neurocognitive aging and dementia risk in the era of climate change.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Socio-environmental and health-related factors and their association with longitudinal change in brain neuroimaging markers through the plasma metabolome among UK adults: An additive Bayesian network analysis.Brain, behavior, & immunity - health · 2025Article
- Living in a 20-min neighborhood and brain health and resilience in older adults: The Healthy Brain Initiative.Health & place · 2025Article
- The Independent and Interactive Effects of Economic Stability and Healthcare Access on 10-Year Cognitive Trajectories of Black/African American and White Older Adults from the ACTIVE Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Why Your Brain Needs a Walk in the Park: Residential Greenspaces as the Next Frontier in Brain Research and Treatment.Annals of neurosciences · 2024Article
- Social Determinants of Health, Risk and Resilience against Alzheimer's Disease and Related Dementias: The Healthy Brain Initiative.Journal of Alzheimer's disease reports · 2024Article
- Neurosustainability.Frontiers in human neuroscience · 2024Article
- Community Socioeconomic Disadvantage Relates to White Matter Hyperintensity Burden in Mid-to-Late Life Adults.Biopsychosocial science and medicineArticle
- Neighborhood greenspace and neighborhood income associated with white matter grade worsening: Cardiovascular Health Study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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14 authors.
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Abstract
introductionWe examined whether a combined measure of neighborhood greenspace and neighborhood median income was associated with white matter hyperintensity (WMH) and ventricle size changes.
methodsThe sample included 1260 cognitively normal ≥ 65-year-olds with two magnetic resonance images (MRI; ≈ 5 years apart). WMH and ventricular size were graded from 0 (least) to 9 (most) abnormal (worsening = increase of ≥1 grade from initial to follow-up MRI scans). The four-category neighborhood greenspace-income measure was based on median neighborhood greenspace and income values at initial MRI. Multivariable logistic regression tested associations between neighborhood greenspace-income and MRI measures (worsening vs. not).
resultsWhite matter grade worsening was more likely for those in lower greenspace-lower income neighborhoods than higher greenspace-higher income neighborhoods (odds ratio = 1.73; 95% confidence interval = 1.19-2.51). DISCUSSION: The combination of lower neighborhood income and lower greenspace may be a risk factor for worsening white matter grade on MRI. However, findings need to be replicated in more diverse cohorts. HIGHLIGHTS: Population-based cohort of older adults (≥ 65 years) with greenspace and MRI dataCombined measure of neighborhood greenspace and neighborhood income at initial MRIMRI outcomes included white matter hyperintensities (WMH) and ventricular sizeLongitudinal change in MRI outcomes measured approximately 5 years apartWorsening WMH over time more likely for lower greenspace-lower income neighborhoods.
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