SynthesisFrontiers in physiology2023
Sensitivity of cognitive function tests to acute hypoxia in healthy subjects: a systematic literature review.
Synthesis in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 20 citations in OpenAlex.
- Normoxic brain endurance training is associated with cognitive and oculomotor performance during acute hypoxia.European journal of applied physiology · 2026Article
- Cerebral oxygenation and cognitive performance under different acute normobaric hypoxic conditions: a fNIRS study.European journal of applied physiology · 2026Article
- Cerebral Oxygen Budgeting: Network-Level BOLD Dynamics During Acute Hypoxia.bioRxiv : the preprint server for biology · 2026Article
- Graded normobaric hypoxia alters cerebral oxygenation and cognition in middle-aged adults: a single-blind counterbalanced randomized crossover trial.GeroScience · 2026Article
- Graded normobaric hypoxia alters cerebral oxygenation and cognition in middle-aged adults: a single-blind counterbalanced randomized crossover trial.GeroScience · 2026Article
- Effects of acute hypoxic exposure on multiple-object tracking ability of flight trainees.Frontiers in psychology · 2026Article
- Combined Liuzijue and mindful breathing promote greater sustained relaxation than mindful breathing alone in university students with anxiety symptoms.Frontiers in psychology · 2026Article
- Acute normobaric hypoxia as a reversible probe of oxygen-limitation contributions to cognitive aging.Aging brain · 2026Review
- Detrimental Effects of Hypoxia on Cognitive Function: Adaptations, Challenges, and Resilience in Andean Populations.Journal of racial and ethnic health disparities · 2025Article
- Regional variation in cerebral oxygen metabolism during acute severe hypoxia with temporary cognitive impairment.NeuroImage · 2025Article
- Hypoxic Preconditioning Mitigates Acute Hypoxia Induced MS/VDB Cholinergic Cell Loss and Memory Impairments.Aging and disease · 2025Article
- Unraveling the complexity of cognitive impairment following high-altitude exposure: from preclinical animal models to human organoids.Frontiers in neuroscience · 2025Review
- Effect of intermittent normobaric hypoxia on executive functions assessed with different cognitive tests in healthy young subjects.Frontiers in psychology · 2025Article
- Acute Three-Dimensional Hypoxia Regulates Angiogenesis.Advanced healthcare materials · 2025Article
- Adding a sustained attention task to a physically demanding cycling exercise exacerbates neuromuscular fatigue and impairs cognitive performance in both normoxia and hypoxia.European journal of applied physiology · 2024Article
- The effects of acute normobaric hypoxia on standing balance while dual-tasking with and without visual input.European journal of applied physiology · 2024Article
- The time course of hypoxia effects using an aviation survival trainer.Frontiers in cognition · 2024Article
- Functional/dissociative seizures as a neuroenergetic deficit syndrome: a brain economy failure hypothesis.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exposure to hypoxia can lead to cognitive impairment. Therefore, hypoxia may become a safety concern for occupational or recreational settings at altitude. Cognitive tests are used as a tool to assess the degree to which hypoxia affects cognitive performance. However, so many different cognitive tests are used that comparing studies is challenging. This structured literature evaluation provides an overview of the different cognitive tests used to assess the effects of acute hypoxia on cognitive performance in healthy volunteers. Less frequently used similar cognitive tests were clustered and classified into domains. Subsequently, the different cognitive test clusters were compared for sensitivity to different levels of oxygen saturation. A total of 38 articles complied with the selection criteria, covering 86 different cognitive tests. The tests and clusters showed that the most consistent effects of acute hypoxia were found with the Stroop test (where 42% of studies demonstrated significant abnormalities). The most sensitive clusters were auditory/verbal memory: delayed recognition (83%); evoked potentials (60%); visual/spatial delayed recognition (50%); and sustained attention (47%). Attention tasks were not particularly sensitive to acute hypoxia (impairments in 0%-47% of studies). A significant hypoxia level-response relationship was found for the Stroop test (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.