Evidence map›Paper›PMID 37885791›Full record

ArticleBioinformation2023

Prediction of transient and permanent protein interactions using AI methods.

Kiran Kumar A, Syed Mohammad Shayez Karim, Mayank Kumar, Rathore Ravindranath Singh

Abstract read
In one paragraph

Article in Bioinformation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kiran Kumar ADepartment of Bioinformatics, Central University of South Bihar, Gaya, Bihar-824236, India.
Syed Mohammad Shayez KarimDepartment of Bioinformatics, Central University of South Bihar, Gaya, Bihar-824236, India.
Mayank KumarDepartment of Bioinformatics, Central University of South Bihar, Gaya, Bihar-824236, India.
Rathore Ravindranath SinghDepartment of Bioinformatics, Central University of South Bihar, Gaya, Bihar-824236, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein-protein interactions (PPIs) can be classified as permanent or transient interactions based on their stability or lifetime. Understanding the precise details of such protein interactions will pave the way for the discovery of inhibitors and for understanding the nature and function of PPIs. In the present work, 43 relevant physicochemical, geometrical and structural features were calculated for a curated dataset from the literature, comprising of 402 protein-protein complexes of permanent and transient categories, and 5 different Supervised Machine Learning models were developed with

Indexed as

Deep LearningMachine LearningScikit-learnTensor Flow.Transient and Permanent Protein-Protein Interactions

Identifiers

PMID37885791
PMCPMC10598364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.