Evidence map›Paper›PMID 37885721›Full record

ArticleHeliyon2023

Ultraviolet light spectroscopic characterization of ibuprofen acid aggregation in deionized water.

Gregorio Marbán, Amparo Fernández-Pérez, Sonia Álvarez-García

Abstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gregorio MarbánInstituto de Ciencia y Tecnología del Carbono (INCAR-CSIC), c/Francisco Pintado Fe 26, 33011, Oviedo, Spain.
Amparo Fernández-PérezInstituto de Ciencia y Tecnología del Carbono (INCAR-CSIC), c/Francisco Pintado Fe 26, 33011, Oviedo, Spain.
Sonia Álvarez-GarcíaDepartamento de Ingeniería Química y Tecnología del Medio Ambiente, Facultad de Químicas, Universidad de Oviedo, c/Julián Clavería 8, 33006, Oviedo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work provides a description of the aggregation equilibria of ibuprofen acid in deionized water at temperatures between 20 and 40 °C in the 0.1-20.1 ppm concentration range. For this goal, we have made use of UV-Visible spectroscopy. A calculation algorithm was developed to obtain the aggregate orders and thermodynamic parameters from the experimental absorbance values. Monomeric ibuprofen acid was found to be absent in water solutions. In addition to the dimer, two aggregates formed by 32 and 128 monomeric units were found to co-exist in solution at the highest concentration tested. A critical micelle concentration of 7.8 ppm was estimated for this system. The appearance of the first aggregate occurs when the pH drops below the

Indexed as

Aggregation equilibriumBeer-Lambert lawIbuprofen acidSelf-assemblyUV–Visible spectroscopy

Identifiers

PMID37885721
PMCPMC10598541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.