ReviewThe European journal of neuroscience2024
Sleep spindles as neurophysiological biomarkers of schizophrenia.
Review in The European journal of neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Review
- Sleep Spindle Measures in Japanese Patients With Drug-Naïve Schizophrenia Using Standard Polysomnography Data: A Retrospective Pilot Study.Early intervention in psychiatry · 2026Article
- Histamine regulation in shaping spindle refractoriness: a computational modeling study.Journal of computational neuroscience · 2026Article
- Article
- Sleep and wake markers of thalamocortical functioning in early-course psychosis and first-degree relatives.Schizophrenia (Heidelberg, Germany) · 2026Article
- Assessing sleep, cognition and overnight memory performance in neurotypically developing youth in a children's hospital.Frontiers in sleep · 2026Article
- Can Sodium Oxybate Mitigate the Symptoms of Schizophrenia?Current neuropharmacology · 2026Review
- Altered Network Function in Hippocampus After Sub-Chronic Activation of Cannabinoid Receptors in Early Adolescence.International journal of molecular sciences · 2025Article
- Sleep Spindle Abnormalities as Neurophysiological Biomarkers of Schizophrenia Spectrum Disorders: From Cellular Mechanisms and Neural Circuits to Clinical Implications.Biological psychiatry · 2025Review
- Do twitching and twitch-spindle coupling differ between N2 and N3 sleep in 6-month-olds?bioRxiv : the preprint server for biology · 2025Article
- Altered network function in hippocampus after sub-chronic activation of Cannabis receptors in peri-adolescence.bioRxiv : the preprint server for biology · 2025Article
- The Infraslow Fluctuation of Sigma Power During Sleep in Young Individuals with Schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Sleep duration and its associated factors in schizophrenia patients: a large-scale cross-sectional survey.BMC psychiatry · 2025Article
- Article
- A spectrum of altered non-rapid eye movement sleep in schizophrenia.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Schizophrenia (SCZ) is a complex psychiatric disorder characterized by a wide range of clinical symptoms, including disrupted sleep. In recent years, there has been growing interest in assessing alterations in sleep parameters in patients with SCZ. Sleep spindles are brief (0.5-2 s) bursts of 12- to 16-Hz rhythmic electroencephalogram (EEG) oscillatory activity occurring during non-rapid eye movement (NREM) sleep. Spindles have been implicated in several critical brain functions, including learning, memory and plasticity, and are thought to reflect the integrity of underlying thalamocortical circuits. This review aims to provide an overview of the current research investigating sleep spindles in SCZ. After briefly describing the neurophysiological features of sleep spindles, I will discuss alterations in spindle characteristics observed in SCZ, their associations with the clinical symptomatology of these patients and their putative underlying neuronal and molecular mechanisms. I will then discuss the utility of sleep spindle measures as predictors of treatment response and disease progression. Finally, I will highlight future directions for research in this emerging field, including the prospect of utilizing sleep spindles as neurophysiological biomarkers of SCZ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.