Evidence map›Paper›PMID 37885112›Full record

ReviewMini reviews in medicinal chemistry2024

Recent Methods for the Synthesis of Quinoxaline Derivatives and their Biological Activities.

Thoraya A Farghaly, Raghad M Alqurashi, Ghada S Masaret, Hanan Gaber Abdulwahab

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Thoraya A FarghalyDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Raghad M AlqurashiDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Ghada S MasaretDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Hanan Gaber AbdulwahabDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Umm al-Qura University · SAAl-Azhar University · EG

Funding

The Deanship for Research and Innovation, Ministry of Education in Saudi Arabia IFP22UQU4350477DSR025
6 · The paper itself

Abstract

Quinoxaline derivatives have been incorporated into numerous marketed drugs used for the treatment of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi), Balversa (L01EX16) (erdafitinib), carbadox, XK469R (NSC698215), and becampanel (AMP397). These quinoxaline derivatives exhibit a diverse range of pharmacological activities, including antibacterial, antitubercular, antiviral, anti-HIV, anti-inflammatory, antifungal, anticancer, antiproliferative, antitumor, kinase inhibition, antimicrobial, antioxidant, and analgesic effects. Recognizing the significance of these bioactive quinoxaline derivatives, researchers have dedicated their efforts to developing various synthetic methods for their production. This review aimed to compile the most recent findings on the synthesis and biological properties of quinoxaline derivatives from 2015 to 2023.

Indexed as

QuinoxalinesAnimalsAnti-Infective AgentsAntineoplastic AgentsAntioxidantsAntiviral AgentsHumansMolecular StructureAnti-Infective AgentsAntineoplastic AgentsAntioxidantsAntiviral AgentsQuinoxalinesanticancerantiviralbiological activitycompound.Quinoxalinesynthesis

Identifiers

PMID37885112
OpenAlexW4387966825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.