Evidence map›Paper›PMID 37884677›Full record

ArticleNature human behaviour2023

Stunting in infancy is associated with atypical activation of working memory and attention networks.

Sobanawartiny Wijeakumar, Samuel H Forbes, Vincent A Magnotta, Sean Deoni, Kiara Jackson, Vinay P Singh, Madhuri Tiwari, Aarti Kumar, John P Spencer

Open access · hybridAbstract read
In one paragraph

Article in Nature human behaviour, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Dynamic Field Theory of Executive Function: Identifying Early Neurocognitive Markers.Monographs of the Society for Research in Child Development · 2024
    Article
  8. Review
  9. Brain-Behavior Associations During Interactions Between Caregivers and Infants.Infancy : the official journal of the International Society on Infant Studies
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sobanawartiny WijeakumarSchool of Psychology, University of Nottingham, Nottingham, UK. sobanawartiny.wijeakumar@nottingham.ac.uk.ORCID 0000-0002-1008-3407
Samuel H ForbesDepartment of Psychology, Durham University, Durham, UK.ORCID 0000-0003-1022-4676
Vincent A MagnottaDepartment of Radiology, University of Iowa, Iowa City, IA, USA.ORCID 0000-0001-8639-5354
Sean DeoniMaternal, Newborn and Child Health Discovery & Tools, Bill & Melinda Gates Foundation, Seattle, WA, USA.
Kiara JacksonSchool of Psychology, University of East Anglia, Norwich, UK.ORCID 0000-0002-1746-3082
Vinay P SinghCommunity Empowerment Lab, Lucknow, India.ORCID 0000-0003-1421-8775
Madhuri TiwariCommunity Empowerment Lab, Lucknow, India.
Aarti KumarCommunity Empowerment Lab, Lucknow, India.ORCID 0000-0003-4331-3747
John P SpencerSchool of Psychology, University of East Anglia, Norwich, UK. j.spencer@uea.ac.uk.ORCID 0000-0002-7320-144X
University of East Anglia · GBDurham University · GBGates Foundation · USUniversity of Iowa · USUniversity of Nottingham · GB

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
Probing the Neural Basis of Visual Working Memory in Early DevelopmentR01HD083287 · NICHD · UNIVERSITY OF EAST ANGLIA · PI SPENCER, JOHN P · 2016 to 2020
$1.9M
NICHD NIH HHS P50 HD103556NICHD NIH HHS R01 HD083287
6 · The paper itself

Abstract

Stunting is associated with poor long-term cognitive, academic and economic outcomes, yet the mechanisms through which stunting impacts cognition in early development remain unknown. In a first-ever neuroimaging study conducted on infants from rural India, we demonstrate that stunting impacts a critical, early-developing cognitive system-visual working memory. Stunted infants showed poor visual working memory performance and were easily distractible. Poor performance was associated with reduced engagement of the left anterior intraparietal sulcus, a region involved in visual working memory maintenance and greater suppression in the right temporoparietal junction, a region involved in attentional shifting. When assessed one year later, stunted infants had lower problem-solving scores, while infants of normal height with greater left anterior intraparietal sulcus activation showed higher problem-solving scores. Finally, short-for-age infants with poor physical growth indices but good visual working memory performance showed more positive outcomes suggesting that intervention efforts should focus on improving working memory and reducing distractibility in infancy.

Indexed as

CognitionMemory, Short-TermGrowth DisordersHumansInfantMemory DisordersProblem Solving

Identifiers

PMID37884677
PMCPMC10730391
OpenAlexW4387965960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.