Evidence map›Paper›PMID 37884605›Full record

ArticleScientific reports2023

A quantitative method for determination of colistin E2 methanesulphonate in human plasma by

Hongjiang Xu, Yanan Li, Jing Zhang, Jinhua Zhang, Jianguang Lu, Xiquan Zhang, Ling Yang, Wenjie Zhao, Jun Feng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hongjiang Xu *China State Institute of Pharmaceutical Industry, Shanghai, China.
Yanan Li *China State Institute of Pharmaceutical Industry, Shanghai, China.
Jing ZhangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Jinhua ZhangChina State Institute of Pharmaceutical Industry, Shanghai, China.
Jianguang LuChina State Institute of Pharmaceutical Industry, Shanghai, China.
Xiquan ZhangChia Tai Tianqing Pharmaceutical Group Co., Ltd., Nanjing, China.
Ling YangChia Tai Tianqing Pharmaceutical Group Co., Ltd., Nanjing, China.
Wenjie ZhaoChina State Institute of Pharmaceutical Industry, Shanghai, China.
Jun FengChina State Institute of Pharmaceutical Industry, Shanghai, China. Fengjdmr@163.com.
Shanghai Institute of Pharmaceutical Industry · CNFudan University · CNShanghai CASB Biotechnology (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The single-component colistin E2, with superior antibacterial activity and lower toxicity, was being developed as the latest generation of polymyxin drugs. However, colistin E2 has not been tested quantitatively in biological matrices. In this study, based on the quantitative detection of colistin methanesulphonate (CMS) and colistin by Zhao et al.,

Indexed as

ColistinTandem Mass SpectrometryAnti-Bacterial AgentsChromatography, High Pressure LiquidHumansMesylatesAnti-Bacterial AgentsColistinMesylates

Identifiers

PMID37884605
PMCPMC10603063
OpenAlexW4387958116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.