ArticleScientific reports2023
Factors influencing extrathyroidal extension of papillary thyroid cancer and evaluation of ultrasonography for its diagnosis: a retrospective analysis.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- The evolving role of MRI in the detection of extrathyroidal extension of papillary thyroid carcinoma: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Diagnostic performance and generalizability of a clinical-ultrasound radiomics model for predicting extrathyroidal extension in thyroid carcinoma: a retrospective study.Annals of medicine · 2026Article
- Preoperative prediction of extrathyroidal extension in papillary thyroid carcinoma: a nomogram integrating dual-plane ultrasound-based radiomics and clinical features.Gland surgery · 2026Article
- Preoperative and Intraoperative Assessment of Extrathyroidal Extension in Unilateral Papillary Thyroid Carcinoma: Does It Necessitate Total Thyroidectomy?Journal of surgical oncology · 2026Article
- Predictive value of a combined nomogram model integrating ultrasound and cytology for 2025 ATA risk stratification of lymph node negative papillary thyroid carcinoma.BMC medical imaging · 2026Article
- Combined clinicopathological and ultrasonographic features for predicting extrathyroidal extension in thyroid cancer.Quantitative imaging in medicine and surgery · 2026Article
- MRI characteristics of cervical radioiodine-avid lymph nodes detected on post-therapeutic ¹³¹I whole-body scintigraphy in differentiated thyroid carcinoma.Frontiers in endocrinology · 2026Article
- Epidemiology, risk factor and prognostic factor of young differentiated thyroid carcinoma with distant metastasis: a retrospective cohort study.American journal of cancer research · 2026Article
- Utility of quantitative contrast-enhanced ultrasound: a valuable prediction for capsule invasion assessment in papillary thyroid cancer.Quantitative imaging in medicine and surgery · 2025Article
- Early prediction of thyroid capsule invasion in papillary microcarcinoma using ultrasound-based deep learning models: a retrospective multicenter study.Insights into imaging · 2025Article
- Prediction model for extrathyroidal extension in thyroid papillary carcinoma based on ultrasound radiomics.Scientific reports · 2025Article
- The predictive value of a combined nomogram model integrating ultrasound and fine-needle aspiration cytology for large-number cervical lymph node metastases in clinically node-negative papillary thyroid carcinoma: a propensity score matching analysis.Quantitative imaging in medicine and surgery · 2025Article
- Comprehensive linkage between molecular biology and imaging radiomics for thyroid nodules.World journal of radiology · 2025Article
- Integration of dual-source dual-energy CT quantitative parameters and ultrasound image features: A diagnostic method for extraglandular invasion of papillary thyroid carcinoma.Oncology letters · 2025Article
- Development and validation of a multidimensional machine learning-based nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma.Gland surgery · 2025Article
- Construction of a predictive model for cervical lymph node metastasis in papillary thyroid carcinoma.Frontiers in oncology · 2025Article
- The diagnostic performance of dual-energy CT imaging in cervical lymph node metastasis of papillary thyroid cancer: a meta-analysis.Frontiers in medicine · 2024Review
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5 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Pathologists usually explore extrathyroidal extensions (ETEs) in thyroid cancer; however, sonographers are often not concerned with ETEs. We investigated factors influencing ETEs and the efficacy of ultrasound evaluation of thyroid capsule invasion. We retrospectively analysed 1933 papillary thyroid carcinoma patients who underwent thyroidectomy during 2018-2021. Patients were divided into three groups: no ETE, minor ETE (mETE), and gross ETE. Clinical characteristic differences were assessed using binary logistic regression analysis to identify ETE predictors, and the kappa test was performed to analyse consistency between ultrasonographic and pathological diagnoses of ETE. The mETE group was more likely to have larger tumour diameters and more extensive lymph node metastasis (LNM) than the no ETE group and more likely to be diagnosed in the isthmus. In the multivariate logistic regression analysis, longest tumour diameter, lesion site, LNM extent, and thyroglobulin concentration were significant mETE predictors. Minimal consistency existed between pathological and ultrasonographic examinations for neighbouring tissue invasion. Many clinical differences were observed between the no ETE and mETE groups, suggesting the importance of considering mETE. Therefore, sonographers should pay more attention to relationships between nodules and capsule and indicate these on ultrasound reports to provide more accurate preoperative ETE information for surgeons.
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