Evidence map›Paper›PMID 37883712›Full record

ArticleEuropean heart journal. Cardiovascular Imaging2024

Automatic measurements of left ventricular volumes and ejection fraction by artificial intelligence: clinical validation in real time and large databases.

Sindre Olaisen, Erik Smistad, Torvald Espeland, Jieyu Hu, David Pasdeloup, Andreas Østvik, Svend Aakhus, Assami Rösner, Siri Malm, Michael Stylidis and 4 more

Open access · hybridAbstract read
In one paragraph

Article in European heart journal. Cardiovascular Imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Sindre OlaisenCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0009-0005-7931-4145
Erik SmistadCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0000-0002-7258-4709
Torvald EspelandCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0000-0002-9243-0176
Jieyu HuCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.
David PasdeloupCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0000-0002-0160-1268
Andreas ØstvikCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.
Svend AakhusCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.
Assami RösnerDepartment of Cardiology, University Hospital of North Norway, Tromsø, Norway.
Siri MalmInstitute for Clinical Medicine, UiT, The Arctic University of Norway, Tromsø, Norway.
Michael StylidisDepartment of Cardiology, University Hospital of North Norway, Tromsø, Norway.
Espen HolteCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0000-0002-8891-1372
Bjørnar GrenneCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.
Lasse LøvstakkenCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.
Havard DalenCentre for Innovative Ultrasound Solutions, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Prinsesse Kristinas Gate 3, 7030 Trondheim, Norway.ORCID 0000-0003-1192-3663
Norwegian University of Science and Technology · NOUniversity Hospital of North Norway · NOSINTEF · NO

Funding

Central Norway Health AuthorityNord-Trøndelag Hospital TrustNorwegian University of Science and TechnologyResearch Council of NorwaySimon Fougner Hartmann Family FoundationSt. Olavs University Hospital
6 · The paper itself

Abstract

aimsEchocardiography is a cornerstone in cardiac imaging, and left ventricular (LV) ejection fraction (EF) is a key parameter for patient management. Recent advances in artificial intelligence (AI) have enabled fully automatic measurements of LV volumes and EF both during scanning and in stored recordings. The aim of this study was to evaluate the impact of implementing AI measurements on acquisition and processing time and test-retest reproducibility compared with standard clinical workflow, as well as to study the agreement with reference in large internal and external databases. METHODS AND

resultsFully automatic measurements of LV volumes and EF by a novel AI software were compared with manual measurements in the following clinical scenarios: (i) in real time use during scanning of 50 consecutive patients, (ii) in 40 subjects with repeated echocardiographic examinations and manual measurements by 4 readers, and (iii) in large internal and external research databases of 1881 and 849 subjects, respectively. Real-time AI measurements significantly reduced the total acquisition and processing time by 77% (median 5.3 min, P < 0.001) compared with standard clinical workflow. Test-retest reproducibility of AI measurements was superior in inter-observer scenarios and non-inferior in intra-observer scenarios. AI measurements showed good agreement with reference measurements both in real time and in large research databases.

conclusionThe software reduced the time taken to perform and volumetrically analyse routine echocardiograms without a decrease in accuracy compared with experts.

Indexed as

Artificial IntelligenceVentricular Dysfunction, LeftEchocardiographyHumansReproducibility of ResultsStroke VolumeVentricular Function, Leftdeep learningechocardiographymachine learningobserver variabilityreproducibilitysystolic function

Identifiers

PMID37883712
PMCPMC11024810
OpenAlexW4387965153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.