Evidence map›Paper›PMID 37883564›Full record

ArticleScience (New York, N.Y.)2023

Genome editing with retroelements.

Stephen Tang, Samuel H Sternberg

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Gene Therapy Techniques and Delivery Methods (Review).Sovremennye tekhnologii v meditsine · 2025
    Review
  11. Article
  12. Article
  13. De novo gene synthesis by an antiviral reverse transcriptase.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen TangDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Samuel H SternbergDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Funding

Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human DiseaseRM1HG009490 · NHGRI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI Brittany S. Adamson, Martin Joseph Ankrah Aryee · 2017 to 2026
$22.7M
Medical Scientist Training ProgramT32GM145440 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEVEN L REINER · 2022 to 2026
$7.3M
Leveraging Programmable Integrases for Human Genome EngineeringDP2HG011650 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERNBERG, SAMUEL HENRY · 2020 to 2020
$2.4M
NHGRI NIH HHS DP2 HG011650NHGRI NIH HHS RM1 HG009490NIGMS NIH HHS T32 GM145440
6 · The paper itself

Abstract

RNA-guided DNA writing enzymes offer promise for programmable gene insertion.

Indexed as

CRISPR-Associated Protein 9Gene EditingMutagenesis, InsertionalRetroelementsRNA, Guide, CRISPR-Cas SystemsCRISPR-Cas SystemsGenome, HumanHumansCRISPR-Associated Protein 9RetroelementsRNA, Guide, CRISPR-Cas Systems

Identifiers

PMID37883564
PMCPMC10727090

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.