Evidence map›Paper›PMID 37883415›Full record

ArticlePloS one2023

Prevalence and risk factors of Toxoplasma gondii infection among women with miscarriage and their aborted fetuses in the northwest of Iran.

Shiva Zeinali, Shahram Khademvatan, Rasool Jafari, Shabnam Vazifekhah, Elham Yousefi, Tahereh Behroozi-Lak

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Transplacental Infection: Frequency, Testing, and Treatment.Deutsches Arzteblatt international · 2026
    Review
  2. Article
  3. Beyond Latency: ChronicBiomedicines · 2025
    Review
  4. Article
  5. Diseases Caused by and Behaviors Associated withPathogens (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Seroprevalence and Risk Factors forIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shiva ZeinaliDepartment of Medical Parasitology and Mycology& Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Shahram KhademvatanDepartment of Medical Parasitology and Mycology& Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.ORCID 0000-0002-8753-0666
Rasool JafariDepartment of Medical Parasitology and Mycology& Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Shabnam VazifekhahMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Elham YousefiDepartment of Medical Parasitology and Mycology& Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Tahereh Behroozi-LakReproductive Health Research Center, Department of Infertility, Urmia University of Medical Sciences, Urmia, Iran.
Urmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is a worldwide disease of various animals and human and results from infection with the Toxoplasma gondii parasite. Abortion and congenital defects are important consequences of the T. gondii infection. The aim of this study was to determine the Toxoplasma-induced abortions among women with miscarriage and the presence of T. gondii in their aborted fetuses in Urmia, the northwest of Iran. This cross-sectional study was conducted with 215 women with abortion and their aborted fetuses, from 2020 to 2021. Seroprevalence of anti-Toxoplasma IgG and IgM were determined using the sera of the aforesaid women. Nested PCR was carried out using RE-529 gene sequences, and sequencing was performed using the T. gondii GRA6 gene on the remnant of pregnancy after abortion. The tissue positive samples were then subjected to another PCR on GRA6 gene and sequenced for genotyping. Among 215 serum samples of women with abortion, 70 (32.6%) were positive for anti-Toxoplasma IgG, and three (1.4%) were positive for IgM. The RE-529 sequence of T. gondii was positive in three (1.4%) of the aborted fetuses. The analysis of GRA6 gene indicated that all three positive samples carried a GRA6 allele (GRA6I) of T. gondii type I genotype. Our findings suggest that T. gondii is one of the causative agents of spontaneous abortion in West Azerbijan Province, the northwest of Iran.

Indexed as

Abortion, SpontaneousToxoplasmaToxoplasmosisAborted FetusAnimalsAntibodies, ProtozoanCross-Sectional StudiesFemaleHumansImmunoglobulin GImmunoglobulin MIranPregnancyPrevalenceRisk FactorsSeroepidemiologic StudiesAntibodies, ProtozoanImmunoglobulin GImmunoglobulin M

Identifiers

PMID37883415
PMCPMC10602335
OpenAlexW4387952698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.