Evidence map›Paper›PMID 37882897›Full record

ArticleJournal of autism and developmental disorders2024

Decreased Functional and Structural Connectivity is Associated with Core Symptom Improvement in Children with Autism Spectrum Disorder After Mini-basketball Training Program.

Dongyue Zhou, Zhimei Liu, Guanyu Gong, Yunge Zhang, Lin Lin, Kelong Cai, Huashuai Xu, Fengyu Cong, Huanjie Li, Aiguo Chen

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Dongyue Zhou *School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Zhimei Liu *College of Physical Education, Yangzhou University, Yangzhou, China.
Guanyu GongDepartment of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Yunge ZhangSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Lin LinSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Kelong CaiCollege of Physical Education, Yangzhou University, Yangzhou, China.
Huashuai XuFaculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland.
Fengyu CongSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Huanjie LiSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China. hj_li@dlut.edu.cn.ORCID http://orcid.org/0000-0002-1056-1579
Aiguo ChenCollege of Physical Education, Yangzhou University, Yangzhou, China. agchen@yzu.edu.cn.
Dalian University of Technology · CNYangzhou University · CNAffiliated Zhongshan Hospital of Dalian University · CNUniversity of Jyväskylä · FIYangzhou Vocational University · CN

Funding

Science and Technology Planning Project of Liaoning Province no. 2022JH2/10700002Scientific research and practice innovation Project of Jiangsu Province 3161The fifth "333 Project" scientific research funding project of Jiangsu Province BRA2019283
6 · The paper itself

Abstract

Exercise intervention has been proven helpful to ameliorate core symptoms of Autism Spectrum Disorder (ASD). However, the underlying mechanisms are not fully understood. In this study, we carried out a 12-week mini-basketball training program (MBTP) on ASD children and examined the changes of brain functional and structural networks before and after exercise intervention. We applied individual-based method to construct functional network and structural morphological network, and investigated their alterations following MBTP as well as their associations with the change in core symptom. Structural MRI and resting-state functional MRI data were obtained from 58 ASD children aged 3-12 years (experiment group: n = 32, control group: n = 26). ASD children who received MBTP intervention showed several distinguishable alternations compared to the control without special intervention. These included decreased functional connectivity within the sensorimotor network (SM) and between SM and the salience network, decreased morphological connectivity strength in a cortical-cortical network centered on the left inferior temporal gyrus, and a subcortical-cortical network centered on the left caudate. Particularly, the aforementioned functional and structural changes induced by MBTP were associated with core symptoms of ASD. Our findings suggested that MBTP intervention could be an effective approach to improve core symptoms in ASD children, decrease connectivity in both structure and function networks, and may drive the brain change towards normal-like neuroanatomy.

Indexed as

Autism Spectrum DisorderBrainMagnetic Resonance ImagingChildChild, PreschoolExercise TherapyFemaleHumansMaleAutism spectrum disorder (ASD)Exercise interventionFunctional connectivityK-meansMorphological brain network

Identifiers

PMID37882897
OpenAlexW4387949101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.