Evidence map›Paper›PMID 37882666›Full record

ArticleeLife2023

Association between

Lan Jiang, Ge Liu, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Adriana M Hung, Nancy J Cox, Cecilia P Chung, Wei-Qi Wei and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Lan JiangDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.
Ge LiuDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, United States.
Annette OeserDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.
Andrea IhegwordDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.
Alyson L DicksonDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.ORCID 0000-0003-3404-3802
Laura L DanielDivision of Rheumatology, Department of Medicine, University of Miami, Miami, United States.ORCID 0000-0003-3143-5915
Adriana M HungTennessee Valley Healthcare System, Nashville Campus, Nashville, United States.
Nancy J CoxVanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.
Cecilia P ChungDivision of Rheumatology, Department of Medicine, University of Miami, Miami, United States.
Wei-Qi WeiDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, United States.
C Michael SteinDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.
Qiping FengDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, United States.ORCID 0000-0002-6213-793X
Vanderbilt University Medical Center · USUniversity of Miami · USVanderbilt University · USVA Tennessee Valley Healthcare System · US

Funding

Genetics and Triglycerides: opportunities for new approaches to identify therapiesR01HL163854 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FENG, QIPING · 2022 to 2025
$3.1M
Targeting Residual ASCVD Risk by Integrating Genetics and Clinical DataR01HL171809 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Qiping Feng, Wei-Qi Wei · 2024 to 2026
$2.6M
Pleiotropy of PCSK9 InhibitionR01GM120523 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FENG, QIPING · 2016 to 2020
$1.7M
Pharmacogenetics to improve drug therapyR35GM131770 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STEIN, CHARLES M. · 2019 to 2023
$1.7M
Exploring Statin Pleiotropic Effects within a Very Large EHR Cohort - Diversity SupplementR01HL133786 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEI, WEI-QI · 2017 to 2020
$1.7M
NHLBI NIH HHS R01 HL133786NHLBI NIH HHS R01 HL163854NHLBI NIH HHS R01HL163854NHLBI NIH HHS R01 HL171809NIGMS NIH HHS R01 GM120523NIGMS NIH HHS R01GM120523NIGMS NIH HHS R35 GM131770NIGMS NIH HHS R35GM131770
6 · The paper itself

Abstract

Background: Two risk variants in the apolipoprotein L1 gene ( Methods: A retrospective cohort study of 2242 Black patients hospitalized with infections. We assessed whether carriage of Results: Of 2242 Black patients hospitalized with infections, 565 developed sepsis. Patients with high-risk Conclusions: Funding: This study was supported by R01GM120523 (QF), R01HL163854 (QF), R35GM131770 (CMS), HL133786 (WQW), and Vanderbilt Faculty Research Scholar Fund (QF). The dataset(s) used for the analyses described were obtained from Vanderbilt University Medical Center's BioVU which is supported by institutional funding, the 1S10RR025141-01 instrumentation award, and by the CTSA grant UL1TR0004from NCATS/NIH. Additional funding provided by the NIH through grants P50GM115305 and U19HL065962. The authors wish to acknowledge the expert technical support of the VANTAGE and VANGARD core facilities, supported in part by the Vanderbilt-Ingram Cancer Center (P30 CA068485) and Vanderbilt Vision Center (P30 EY08126). The funders had no role in design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Indexed as

Apolipoprotein L1Kidney DiseasesSepsisBlack or African AmericanGenotypeHumansRetrospective StudiesAPOL1 protein, humanApolipoprotein L1African ancestryAPOL1electronic health recordsgeneticsgenomicshumanmedicinesepsis

Identifiers

PMID37882666
PMCPMC10602586
OpenAlexW4382398514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.