Evidence map›Paper›PMID 37882531›Full record

ArticleInfection and immunity2023

Bladder-draining lymph nodes support germinal center B cell responses during urinary tract infection in mice.

Sophia Hawas, Dimitrios Vagenas, Ashraful Haque, Makrina Totsika

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The immune mechanisms of the urinary tract against infections.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sophia HawasCentre for Immunology and Infection Control, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology , Brisbane, Queensland, Australia.ORCID 0000-0002-6505-462X
Dimitrios VagenasResearch Methods Group, School of Public Health and Social Work, Faculty of Health, Queensland University of Technology , Brisbane, Queensland, Australia.
Ashraful HaqueCentre for Immunology and Infection Control, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology , Brisbane, Queensland, Australia.ORCID 0000-0003-2260-0026
Makrina TotsikaCentre for Immunology and Infection Control, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology , Brisbane, Queensland, Australia.ORCID 0000-0003-2468-0293
Queensland University of Technology · AU

Funding

Australian Government (Federal Government) Research Training Program ScholarshipDepartment of Education and Training | Australian Research Council (ARC) Georgina Sweet Award for Women in Quantitative Biomedical ScienceDHAC | National Health and Medical Research Council (NHMRC) GNT1144046Queensland University of Technology (QUT) Faculty of Health Collaborative Seed GrantRamaciotti Foundations (RF) 2017HIG0119
6 · The paper itself

Abstract

Bacterial urinary tract infections (UTIs) are both common and exhibit high recurrence rates in women. UTI healthcare costs are increasing due to the rise of multidrug-resistant (MDR) bacteria, necessitating alternative approaches for infection control. Here, we directly observed host adaptive immune responses in acute UTI. We employed a mouse model in which wild-type C57BL/6J mice were transurethrally inoculated with a clinically relevant MDR UTI strain of uropathogenic

Indexed as

Escherichia coli InfectionsUrinary TractUrinary Tract InfectionsUropathogenic Escherichia coliAnimalsFemaleGerminal CenterHumansMiceMice, Inbred C57BLUrinary Bladderadaptive immunityB-cell responsesbladderflow cytometrygerminal centerlymph nodesmultidrug resistanceUPECurineUTI

Identifiers

PMID37882531
PMCPMC10652902
OpenAlexW4387950204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.