Evidence map›Paper›PMID 37882516›Full record

ArticlemSphere2023

Genomic epidemiology reveals the dominance of Hennepin County in the transmission of SARS-CoV-2 in Minnesota from 2020 to 2022.

Matthew Scotch, Kimberly Lauer, Eric D Wieben, Yesesri Cherukuri, Julie M Cunningham, Eric W Klee, Jonathan J Harrington, Julie S Lau, Samantha J McDonough, Mark Mutawe and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Matthew ScotchResearch Affiliate, Mayo Clinic, Phoenix, Arizona, USA.ORCID 0000-0001-5100-9724
Kimberly LauerDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Eric D WiebenDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
Yesesri CherukuriResearch Services, Mayo Clinic, Jacksonville, Florida, USA.
Julie M CunninghamDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Eric W KleeDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Jonathan J HarringtonCenter for Individualized Medicine, Rochester, Minnesota, USA.
Julie S LauCenter for Individualized Medicine, Rochester, Minnesota, USA.
Samantha J McDonoughCenter for Individualized Medicine, Rochester, Minnesota, USA.
Mark MutaweCenter for Individualized Medicine, Rochester, Minnesota, USA.
John C O'HoroDivision of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Chad E RentmeesterDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Nicole R SchlicherDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Valerie T WhiteDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Susan K SchneiderDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Peter T VedellDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Xiong WangMinnesota Department of Health, St. Paul, Minnesota, USA.
Joseph D YaoDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Bobbi S PrittDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-0261-1326
Andrew P NorganDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-2955-2066
Mayo Clinic · USMayo Clinic in Florida · USMinnesota Department of Health · USWinnMed · US

Funding

Enriching SARS-CoV-2 sequence data in public repositories with information extracted from full text articlesR01AI164481 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI GONZALEZ HERNANDEZ, GRACIELA, SCOTCH, MATTHEW · 2021 to 2023
$1.9M
NIAID NIH HHS R01 AI164481
6 · The paper itself

Abstract

importanceWe analyzed over 22,000 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes of patient samples tested at Mayo Clinic Laboratories during a 2-year period in the COVID-19 pandemic, which included Alpha, Delta, and Omicron variants of concern to examine the roles and relationships of Minnesota virus transmission. We found that Hennepin County, the most populous county, drove the transmission of SARS-CoV-2 viruses in the state after including the formation of earlier clades including 20A, 20C, and 20G, as well as variants of concern Alpha and Delta. We also found that Hennepin County was the source for most of the county-to-county introductions after an initial predicted introduction with the virus in early 2020 from an international source, while other counties acted as transmission "sinks." In addition, major policies, such as the end of the lockdown period in 2020 or the end of all restrictions in 2021, did not appear to have an impact on virus diversity across individual counties.

Indexed as

COVID-19SARS-CoV-2Communicable Disease ControlGenomicsHumansMinnesotaPandemicscomputational biologyepidemiologyhigh-throughput nucleotide sequencingMinnesotaSARS-CoV-2

Identifiers

PMID37882516
PMCPMC10871168
OpenAlexW4387950096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.