ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Maximizing utility of neuropsychological measures in sex-specific predictive models of incident Alzheimer's disease in the Framingham Heart Study.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Psychometric modeling of Boston process approach data for dementia prediction in the Framingham Heart Study.Journal of the International Neuropsychological Society : JINS · 2026Article
- Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study.Journal of medical Internet research · 2025Observational
- Alzheimer disease seen through the lens of sex and gender.Nature reviews. Neurology · 2025Review
- Atrophy trajectories in Alzheimer's disease: how sex matters.Alzheimer's research & therapy · 2025Article
- Midlife financial stress and cognitive and physical impairments in older age: The role of potentially modifying factors.Social science & medicine (1982) · 2025Article
- Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults.Scientific reports · 2025Article
- Dynamic lifetime risk prediction of Alzheimer's disease with longitudinal cognitive assessment measurements.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Identifying proteomic prognostic markers for Alzheimer's disease with survival machine learning: The Framingham Heart Study.The journal of prevention of Alzheimer's disease · 2025Article
- Exploring sex differences in Alzheimer's disease: a comprehensive analysis of a large patient cohort from a memory unit.Alzheimer's research & therapy · 2025Observational
- Identifying Proteomic Prognostic Markers for Alzheimer's Disease with Survival Machine Learning: the Framingham Heart Study.medRxiv : the preprint server for health sciences · 2024Article
- Maximizing utility of neuropsychological measures in sex-specific predictive models of incident Alzheimer's disease in the Framingham Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Editorial: Cognitive assessment in facilitating early detection of dementia.Frontiers in dementia · 2024Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionSex differences in neuropsychological (NP) test performance might have important implications for the diagnosis of Alzheimer's disease (AD). This study investigates sex differences in neuropsychological performance among individuals without dementia at baseline.
methodsNeuropsychological assessment data, both standard test scores and process coded responses, from Framingham Heart Study participants were analyzed for sex differences using regression model and Cox proportional hazards model. Optimal NP profiles were identified by machine learning methods for men and women.
resultsSex differences were observed in both summary scores and composite process scores of NP tests in terms of adjusted means and their associations with AD incidence. The optimal NP profiles for men and women have 10 and 8 measures, respectively, and achieve 0.76 mean area under the curve for AD prediction. DISCUSSION: These results suggest that NP tests can be leveraged for developing more sensitive, sex-specific indices for the diagnosis of AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.