Evidence map›Paper›PMID 37882064›Full record

ArticleMolecular and cellular biology2023

A SNAI2/CTCF Interaction is Required for

Prethish Sreenivas, Long Wang, Meng Wang, Anil Challa, Paulomi Modi, Nicole Rae Hensch, Berkley Gryder, Hsien-Chao Chou, Xiang R Zhao, Benjamin Sunkel and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. TAD-dependent sub-TAD is required for enhancer-promoter interaction enabling the β-globin transcription.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Prethish SreenivasGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.ORCID 0000-0002-1260-4464
Long WangGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Meng WangCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio, USA.
Anil ChallaGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Paulomi ModiGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Nicole Rae HenschGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Berkley GryderDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Hsien-Chao ChouGenetics Branch, NIH, Bethesda, Maryland, USA.
Xiang R ZhaoGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Benjamin SunkelCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio, USA.
Rodrigo Moreno-CamposGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.
Javed KhanPediatric Oncology Branch, NCI, NIH, Bethesda, Maryland, USA.
Benjamin Z StantonCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio, USA.
Myron S IgnatiusGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Sciences Center, San Antonio, Texas, USA.ORCID 0000-0001-6639-7707
The University of Texas Health Science Center at San Antonio · USNationwide Children's Hospital · USCase Western Reserve University · USNational Institutes of Health · US

Funding

A role for notch in self renewal in embryonal rhabdomyosarcomaR00CA175184 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IGNATIUS, MYRON STEVE · 2017 to 2019
$747k
Characterizing contemporary practices in the approach to elevated troponin I levels during sepsisF32HL160062 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GARCIA, MICHAEL ANTHONY · 2021 to 2021
$54k
NCI NIH HHS R00 CA175184NHLBI NIH HHS F32 HL160062NHLBI NIH HHS L30 HL170345
6 · The paper itself

Abstract

Rhabdomyosarcoma (RMS) is a pediatric malignancy of the muscle with characteristics of cells blocked in differentiation.

Indexed as

ChromatinRhabdomyosarcomaCCCTC-Binding FactorChildHumansReceptor, Notch1RNA, Small InterferingSnail Family Transcription FactorsCCCTC-Binding FactorChromatinCTCF protein, humanNOTCH1 protein, humanReceptor, Notch1RNA, Small InterferingSNAI2 protein, humanSnail Family Transcription FactorsChIP-seqChromatinCRISPR/Cas9CTCFgene regulationHiCNotchNOTCH1RhabdomyosarcomaSNAI2

Identifiers

PMID37882064
PMCPMC10761179
OpenAlexW4387950515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.