Evidence map›Paper›PMID 37881600›Full record

ArticleBiomedical reports2023

When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients.

Konstantinos Faropoulos, Ifigeneia Gioti, Vasiliki Epameinondas Georgakopoulou, Demetrios A Spandidos, Petros Papalexis, Ioannis G Lempesis, Nikolaos Trakas, Ilias Trakas, Andreas Anagiotos, George Fotakopoulos

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In one paragraph

Article in Biomedical reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Konstantinos FaropoulosDepartment of Neurosurgery, Nicosia General Hospital, 2029 Nicosia, Cyprus.
Ifigeneia GiotiDepartment of Radiotherapy, University Hospital of Patras, 26504 Patras, Greece.
Vasiliki Epameinondas GeorgakopoulouDepartment of Pathophysiology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Petros PapalexisUnit of Endocrinology, First Department of Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Ioannis G LempesisDepartment of Pathophysiology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Nikolaos TrakasDepartment of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece.
Ilias TrakasDepartment of Pathophysiology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Andreas AnagiotosDepartment of Otolaryngology, Nicosia General Hospital, 2029 Nicosia, Cyprus.
George FotakopoulosDepartment of Neurosurgery, General University Hospital of Larissa, 41221 Larissa, Greece.
National and Kapodistrian University of Athens · GRNicosia General Hospital · CYSismanoglio General Hospital · GRGeneral University Hospital of Patras · GRUniversity Hospital of Larissa · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the increase in life expectancy, the number of elderly patients suffering from a pituitary macroadenoma is expected to increase in the future. The endoscopic endonasal transsphenoidal (EET) approach tends to be the first choice for the treatment of pituitary macroadenomas in the general population. Notwithstanding, in the geriatric population, the goals of management for this condition remain unclear. The present study retrospectively evaluated and describes the cases of 6 patients >70 years of age with a pituitary macroadenoma who were treated by a skull base team, composed of one ENT surgeon and one neurosurgeon. All the patients experienced a notable improvement in their neurological deficit, while their hormonal status also improved or at least did not deteriorate after the surgery. The EET approach appears to be a safe and effective approach for the treatment of pituitary macroadenomas in the geriatric population.

Indexed as

elderlyendoscopic endonasal transsphenoidal approachgeriatric populationpituitary macroadenomassurgery

Identifiers

PMID37881600
PMCPMC10594072
OpenAlexW4387309661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.