Evidence map›Paper›PMID 37881469›Full record

ArticleNIHR open research2023

Comparison of clinical outcomes between active and permissive blood pressure management in extremely preterm infants.

Narendra Aladangady, Ajay Sinha, Jayanta Banerjee, Felix Asamoah, Asha Mathew, Phillippa Chisholm, Steven Kempley, Joan Morris

Abstract read
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In one paragraph

Article in NIHR open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Monitoring and evaluation of hypotension in the extremely preterm.Frontiers in cardiovascular medicine · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Narendra AladangadyDepartment of Neonatology, Homerton University Hospital, Homerton Healthcare NHS Foundation Trust, London, E9 6SR, UK.ORCID https://orcid.org/0000-0001-9140-4278
Ajay SinhaCentre for Paediatrics, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0001-5201-7718
Jayanta BanerjeeDepartment of Neonatology, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0002-7765-8439
Felix AsamoahDepartment of Statistics, NHS England and Improvement, London, UK.
Asha MathewDepartment of Neonatology, Homerton University Hospital, Homerton Healthcare NHS Foundation Trust, London, E9 6SR, UK.
Phillippa ChisholmDepartment of Neonatology, Homerton University Hospital, Homerton Healthcare NHS Foundation Trust, London, E9 6SR, UK.ORCID https://orcid.org/0000-0001-7381-8776
Steven KempleyCentre for Paediatrics, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-4080-3700
Joan MorrisEnvironment, Prevention & Health Care, Population Health Research Institute, St George's University of London, London, UK.ORCID https://orcid.org/0000-0002-7164-612X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There remains uncertainty about the definition of normal blood pressure (BP), and when to initiate treatment for hypotension for extremely preterm infants. To determine the short-term outcomes of extremely preterm infants managed by active compared with permissive BP support regimens during the first 72 hours of life. Method: This is a retrospective medical records review of 23 Results: There were 764 infants admitted to the participating hospitals; 671 (88%) were included in the analysis (263 Conclusions: There was no difference in mortality or IVH between the two BP management approaches. Active BP support may reduce NEC. This should be investigated prospectively in large multicentre randomised studies.

Indexed as

Active BP supportBlood pressureHypotensionPermissive BP supportPreterm infants

Identifiers

PMID37881469
PMCPMC10593335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.