Evidence map›Paper›PMID 37881468›Full record

ArticleNIHR open research2023

Development of an online intervention for the Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN (REGAIN) trial.

Stuart Ennis, Peter Heine, Harbinder Sandhu, Bart Sheehan, Joyce Yeung, David McWilliams, Christina Jones, Charles Abraham, Martin Underwood, Julie Bruce and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NIHR open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Stuart EnnisClinical Trials Unit, University of Warwick, Coventry, UK.
Peter HeineClinical Trials Unit, University of Warwick, Coventry, UK.
Harbinder SandhuClinical Trials Unit, University of Warwick, Coventry, UK.
Bart SheehanThe Oxford Psychological Medicine Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Joyce YeungClinical Trials Unit, University of Warwick, Coventry, UK.ORCID https://orcid.org/0000-0003-2950-4758
David McWilliamsCentre for Care Excellence, Coventry University, Coventry, UK.ORCID https://orcid.org/0000-0002-9086-2557
Christina JonesICUsteps Peer Support Charity, ICUsteps Peer Support Charity, London, UK.
Charles AbrahamSchool of Psychology, Deakin University, Melbourne, Australia.
Martin UnderwoodClinical Trials Unit, University of Warwick, Coventry, UK.
Julie BruceClinical Trials Unit, University of Warwick, Coventry, UK.ORCID https://orcid.org/0000-0002-8462-7999
Kate SeersHealth Sciences, University of Warwick, Coventry, UK.ORCID https://orcid.org/0000-0001-7921-552X
Gordon McGregorClinical Trials Unit, University of Warwick, Coventry, UK.ORCID https://orcid.org/0000-0001-8963-9107
University of Warwick · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBCoventry University · GBDeakin University · AUOxford University Hospitals NHS Trust · GBSisters of Charity Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Up to half of people hospitalised with COVID-19 report diverse and persistent symptoms affecting quality of life for months and sometimes years after discharge (long-COVID). We describe the development of an online group exercise and behavioural support intervention for people who continue to experience such physical and/or emotional health problems more than three months after hospital discharge. Methods: Intervention development was informed by the Medical Research Council framework for complex interventions. Our multidisciplinary team of academics, clinicians, and people with long-COVID, had collective expertise in the development and testing of complex interventions. We integrated a bio-psycho-social model of care drawing on rehabilitation literature for long-term health conditions and experiences from our pre-pilot study. Multiple stakeholder meetings were held to refine the intervention which was designed to be deliverable within the UK National Health Service. We adhere to TIDieR guidance for transparent and explicit reporting of telehealth interventions. Results: The final REGAIN online exercise and behavioural support intervention consisted of an initial 1:1 consultation with a trained practitioner, followed by eight online group exercise, and six group support, sessions delivered over eight weeks. Participants could also access an online library of on-demand exercise and support videos. Conclusions: The final REGAIN intervention, combining exercise and behavioural support, is fully manualised with clear pathways to delivery and implementation. It is currently being tested in a randomised controlled trial. The intervention, developed with extensive patient and stakeholder engagement, could be incorporated into existing NHS rehabilitation programmes, should it prove to be clinically and cost-effective for people with long-COVID. Trial registration: International Standard Randomised Controlled Trial Number (ISRCTN) 11466448: Rehabilitation exercise and psychological support after COVID-19 infection: REGAIN.

Indexed as

intervention developmentlong-COVIDonline supportphysical activityrehabilitation

Identifiers

PMID37881468
PMCPMC10593321
OpenAlexW4384340172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.