Evidence map›Paper›PMID 37881401›Full record

ArticleCureus2023

Rare Cause of Skull Base Osteomyelitis: A Challenging Diagnosis and Management With a Literature Review.

Syed Zohaib Maroof Hussain, Ibrahim I Haq, Zaki Arshad, Ayomide Ekunola, Sudip Das

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Scedosporium Apiospermum: A Rare Cause of Necrotizing Otitis Externa. Our Experience and A Review of the Current Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Syed Zohaib Maroof HussainEar, Nose and Throat (ENT), Leicester Royal Infirmary, Leicester, GBR.
Ibrahim I HaqEar, Nose and Throat (ENT), University Hospitals of Leicester NHS (National Health Service) Trust, Leicester, GBR.
Zaki ArshadTrauma and Orthopaedic Surgery, Cambridge University School of Clinical Medicine, Cambridge, GBR.
Ayomide EkunolaEar, Nose and Throat (ENT), Leicester Royal Infirmary, Leicester, GBR.
Sudip DasEar, Nose and Throat (ENT), Leicester Royal Infirmary, Leicester, GBR.
Cambridge School · PTLeicester Royal Infirmary · GBUniversity Hospitals of Leicester NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a case of skull base osteomyelitis (SBO) caused by a rare fungal species, Scedosporium apiospermum. This is a clinical case report with a review of the literature. SBO is a potentially life-threatening infection of the temporal bone. The patient presented to our hospital with a two-month history of left otalgia, otorrhea and reduced hearing, after failed initial intravenous antibiotic therapy. Thorough examination and further investigation confirmed the diagnosis of SBO caused by a rare fungal species, S. apiospermum. The patient was subsequently started on a long-term course of antifungals which led to an improvement of symptoms. This case highlights the importance of early recognition and considering early antifungal treatment in patients with persistent otalgia and otorrhea, particularly in those who have failed to respond to intravenous antibiotics. Further research is needed to better understand the optimal timing and duration of antifungal therapy in these patients.

Indexed as

fungal ear infectionmalignant otitis externanecrotizing otitis externascedosporium apiospermumskull base osteomyelitis

Identifiers

PMID37881401
PMCPMC10594066
OpenAlexW4386998066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.