ArticleCureus2023
Comparative Evaluation of Fluoride Release and Compressive Strength of Biodentine Modified Using Sodium Fluorosilicate and Hydrofluoric Acid: An In-Vitro Study.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 citations in OpenAlex.
- Comparative Analysis of the Physical Properties of Three Different Tricalcium Silicate Cements: An In Vitro Study.European journal of dentistry · 2026Article
- Modifications of Biodentine and Their Influence on Endodontic Properties: A Scoping Review.International journal of dentistry · 2026Review
- Bioceramics in Endodontics: Limitations and Future Innovations-A Review.Dentistry journal · 2025Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Calcium trisilicate derivatives have widely been used as dentin and enamel substitutes recently. These cements have excellent biological properties, but they do not show fluoride release. The release of fluoride from dental materials is a very important property of a material in restorative applications as fluoride confers antibacterial and anti-cariogenic properties. This study thus attempts to incorporate fluoride in the form of sodium fluorosilicate and hydrofluoric acid into Biodentine to assess its fluoride-releasing properties. Methods Biodentine was modified by adding 7% sodium fluorosilicate in the powder and 10% hydrofluoric acid to the liquid. Fluoride release was measured using a sodium 2-(parasulfophenylazo)-1,8-dihydroxy-3,6-naphthalenedisulfonate (SPADNS) spectrophotometer after 1, 3, 7, 14, 21, and 28 days. The compressive strength of the modified material was measured using a universal testing machine. Results Fluoride release was found to be higher in the group that had both powder and liquid modified than in groups in which either of the components were modified. The difference was found to be statistically significant (p<0.001). Conclusion Incorporation of fluoride in Biodentine is feasible with acceptable release of fluoride without adversely affecting the compressive strength of the Biodentine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.