Evidence map›Paper›PMID 37881371›Full record

ArticleJournal of biomedical optics2023

Observation and density estimation of a large number of skin capillaries using wide-field portable video capillaroscopy and semantic segmentation.

Baku Takimoto, Kotatsu Bito, Sayaka Hari, Hiroyuki Taguchi, Hideaki Haneishi

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Baku TakimotoKao Corporation, Analytical Science Research Laboratories, Tokyo, Japan.ORCID 0000-0002-1516-9138
Kotatsu BitoKao Corporation, Digital Business Creation, Corporate Strategy, Tokyo, Japan.ORCID 0000-0002-3197-7880
Sayaka HariKao Corporation, Health and Wellness Products Research Laboratories, Tokyo, Japan.
Hiroyuki TaguchiKao Corporation, R&D Strategy and Planning, Tokyo, Japan.
Hideaki HaneishiChiba University, Center for Frontier Medical Engineering, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Skin capillaries are non-invasively observable; their structure and blood flow can reflect tissue and systemic conditions. Quantitative analysis of video-capillaroscopy images yields novel diagnostic methods. Because the capillary structure is heterogeneous, analyzing more capillaries can increase the evaluation reliability. Aim: We developed a system that can observe and quantify numerous capillaries and verified the performance on human skin. Approach: We developed a portable video-capillaroscope with a spatial resolution higher than Results: Over 1000 capillaries were simultaneously observed using the proposed system. Although pixel-level segmentation performance was low [intersection over union (IoU) = 24.5%], the number and area could be estimated. These values differed among four participants and seven sites, and they changed after skin barrier destruction. Conclusions: The proposed system allows for observing and quantifying numerous skin capillaries simultaneously, suggesting its potential for evaluating tissue and systemic conditions.

Indexed as

CapillariesSkin DiseasesHumansMicroscopic AngioscopyReproducibility of ResultsSemanticsSkincapillaroscopydeep learningsemantic segmentationskin capillaryskin microcirculationU-Net

Identifiers

PMID37881371
PMCPMC10594543

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.