Evidence map›Paper›PMID 37880684›Full record

ArticleBMC chemistry2023

[1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase.

Salman Alrokayan, Tajamul Hussain, Salman Alamery, Arif Ahmed Mohammed, Abid Mahmood, Syeda Abida Ejaz, Peter Langer, Jamshed Iqbal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Six Bioactive Small Molecules fromFoods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Salman AlrokayanResearch Chair for Biomedical Application of Nanomaterials, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Tajamul HussainResearch Chair for Biomedical Application of Nanomaterials, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Salman AlameryBiochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Arif Ahmed MohammedBiochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Abid MahmoodCentre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan.
Syeda Abida EjazDepartment of Pharmaceutical Chemistry, Faculty of Pharmacv, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Peter LangerInstitut Für Chemie, Universität Rostock, A.-Einstein-Str. 3a, 18059, Rostock, Germany.
Jamshed IqbalCentre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan. drjamshed@cuiatd.edu.pk.
King Saud University · SAAbbottabad University of Science and Technology · PKCOMSATS University Islamabad · PKIslamia University of Bahawalpur · PKUniversity of Rostock · DE

Funding

Ministry of Education - Kingdom of Saudi Arabi IFKSURC-1-3703
6 · The paper itself

Abstract

[1,8]-Naphthyridine derivatives have been reported to possess important biological activities and may serve as attractive pharmacophores in the drug discovery process. [1,8]-Naphthyridine derivatives (1a-1l) were evaluated for inhibitory potential for isozymes of carbonic anhydrase (CA) and alkaline phosphatase (ALP). CAs have been reported to carry out reversible hydration of CO

Indexed as

[1, 8]-Naphthyridine derivativesAlkaline phosphataseCarbonic anhydraseDFT studiesSimulation studies

Identifiers

PMID37880684
PMCPMC10599030
OpenAlexW4387939644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.