Evidence map›Paper›PMID 37880452›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2024

The effects of rTMS on motor recovery after stroke: a systematic review of fMRI studies.

Zhiqing Tang, Tianhao Liu, Kaiyue Han, Ying Liu, Wenlong Su, Rongrong Wang, Hao Zhang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhiqing TangSchool of Rehabilitation, Capital Medical University, Beijing, China.
Tianhao LiuSchool of Rehabilitation, Capital Medical University, Beijing, China.
Kaiyue HanSchool of Rehabilitation, Capital Medical University, Beijing, China.
Ying LiuSchool of Rehabilitation, Capital Medical University, Beijing, China.
Wenlong SuSchool of Rehabilitation, Capital Medical University, Beijing, China.
Rongrong WangSchool of Rehabilitation, Capital Medical University, Beijing, China.
Hao ZhangSchool of Rehabilitation, Capital Medical University, Beijing, China. crrczh2020@163.com.ORCID http://orcid.org/0000-0001-8193-4101
Capital Medical University · CNQingdao University · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China No. 2021ZX-18the special scientific research project for health development in the capital No.2020-1-6011
6 · The paper itself

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been widely used in motor rehabilitation after stroke, and functional magnetic resonance imaging (fMRI) has been used to investigate the neural mechanisms of motor recovery during stroke therapy. However, there is no review on the mechanism of rTMS intervention for motor recovery after stroke based on fMRI explicitly. We aim to reveal and summarize the neural mechanism of the effects of rTMS on motor function after stroke as measured by fMRI. We carefully performed a literature search using PubMed, EMBASE, Web of Science, and Cochrane Library databases from their respective inceptions to November 2022 to identify any relevant randomized controlled trials. Researchers independently screened the literature, extracted data, and qualitatively described the included studies. Eleven studies with a total of 420 poststroke patients were finally included in this systematic review. A total of 338 of those participants received fMRI examinations before and after rTMS intervention. Five studies reported the effects of rTMS on activation of brain regions, and four studies reported results related to brain functional connectivity (FC). Additionally, five studies analyzed the correlation between fMRI and motor evaluation. The neural mechanism of rTMS in improving motor function after stroke may be the activation and FCs of motor-related brain areas, including enhancement of the activation of motor-related brain areas in the affected hemisphere, inhibition of the activation of motor-related brain areas in the unaffected hemisphere, and changing the FCs of intra-hemispheric and inter-hemispheric motor networks.

Indexed as

Magnetic Resonance ImagingRecovery of FunctionStrokeStroke RehabilitationTranscranial Magnetic StimulationBrainHumansFunctional magnetic resonance imagingMotorRandomized controlled trialsRepetitive transcranial magnetic stimulationStrokeSystematic review

Identifiers

PMID37880452
OpenAlexW4387950070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.