Evidence map›Paper›PMID 37880436›Full record

ArticleNature2023

A microfluidic transistor for automatic control of liquids.

Kaustav A Gopinathan, Avanish Mishra, Baris R Mutlu, Jon F Edd, Mehmet Toner

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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  10. Review
  11. Article
  12. A passive flow microreactor for urine creatinine test.Microsystems & nanoengineering · 2025
    Article
  13. A Machine Vision Perspective on Droplet-Based Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kaustav A GopinathanBioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-4082-1052
Avanish MishraBioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.
Baris R MutluBioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.
Jon F EddBioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.
Mehmet TonerBioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA. mtoner@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-3647-3665
Massachusetts General Hospital · USShriners Hospitals for Children - Erie · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
High-flow microfluidics of leukapheresis blood products for functional analysis of breast circulating tumor cellsR01CA255602 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HABER, DANIEL A., MAHESWARAN, SHYAMALA · 2021 to 2025
$3.2M
Metastasis and biophysics of clusters of circulating tumor cells in the microcirculationU01CA214297 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HABER, DANIEL A., MAHESWARAN, SHYAMALA · 2018 to 2022
$2.9M
Microfluidic sorting of lung cancer cells from leukapheresis product as an alternative to metastatic tumor biopsyR01CA260304 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HABER, DANIEL A., MAHESWARAN, SHYAMALA · 2021 to 2025
$2.2M
Precision Apheresis: stem cell isolation from patients with sickle cell disease for gene therapy using high-throughput microfluidicsK25HL169816 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Avanish Mishra · 2023 to 2026
$550k
Microfluidic Apheresis to Isolate Circulating Tumor ClustersR21CA260989 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2022 to 2023
$428k
NCI NIH HHS R01 CA255602NCI NIH HHS R01 CA260304NCI NIH HHS R21 CA260989NCI NIH HHS U01 CA214297NHLBI NIH HHS K25 HL169816NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

Microfluidics have enabled notable advances in molecular biology

Identifiers

PMID37880436
PMCPMC10600001
OpenAlexW4387950287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.