Evidence map›Paper›PMID 37880369›Full record

ArticleNature2023

An ON-type direction-selective ganglion cell in primate retina.

Anna Y M Wang, Manoj M Kulkarni, Amanda J McLaughlin, Jacqueline Gayet, Benjamin E Smith, Max Hauptschein, Cyrus F McHugh, Yvette Y Yao, Teresa Puthussery

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  15. Cholinergic Waves Have a Modest Influence on the Transcriptome of Retinal Ganglion Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  16. Article
  17. Astrocytes in the mouse brain respond bilaterally to unilateral retinal neurodegeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Frontiers in cell and developmental biology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anna Y M WangHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0000-0001-5075-9187
Manoj M KulkarniHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0000-0003-4694-7366
Amanda J McLaughlinHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.
Jacqueline GayetHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.
Benjamin E SmithHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0000-0003-0141-8145
Max HauptscheinHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0000-0002-8478-568X
Cyrus F McHughHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0000-0002-7965-5733
Yvette Y YaoHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA.ORCID 0009-0004-1420-4570
Teresa PuthusseryHerbert Wertheim School of Optometry and Vision Science, Berkeley, CA, USA. tputhussery@berkeley.edu.ORCID 0000-0002-9188-6067
University of California, Berkeley · USNeurosciences Institute · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
UC Berkeley Vision Science COREP30EY003176 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD H KRAMER · 1985 to 2026
$16.4M
TRAINING PROGRAM IN VISION SCIENCET32EY007043 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Suzanne MJ FLEISZIG · 1985 to 2026
$12.9M
Structure and Function of Primate Retinal CircuitsR01EY024265 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI PUTHUSSERY, TERESA · 2014 to 2025
$4.4M
NEI NIH HHS P30 EY003176NEI NIH HHS R01 EY024265NEI NIH HHS T32 EY007043NIH HHS P51 OD011092NIH HHS P51 OD011107
6 · The paper itself

Abstract

To maintain a stable and clear image of the world, our eyes reflexively follow the direction in which a visual scene is moving. Such gaze-stabilization mechanisms reduce image blur as we move in the environment. In non-primate mammals, this behaviour is initiated by retinal output neurons called ON-type direction-selective ganglion cells (ON-DSGCs), which detect the direction of image motion and transmit signals to brainstem nuclei that drive compensatory eye movements

Indexed as

Eye MovementsMacacaRetinaRetinal Ganglion CellsAnimalsCalcium SignalingFixation, Oculargamma-Aminobutyric AcidHumansMotionPhotic StimulationSingle-Cell Gene Expression Analysisgamma-Aminobutyric Acid

Identifiers

PMID37880369
PMCPMC10632142
OpenAlexW4387948595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.