ArticleScientific reports2023
Visfatin in the porcine pituitary gland: expression and regulation of secretion during the oestrous cycle and early pregnancy.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Unraveling the cytoprotective mechanism of polysaccharides in heat-stressed rabbits: antioxidant, anti-inflammatory, physiological status, and molecular docking assessment.Veterinary research communications · 2026Article
- Irisin modulates the transcriptomic profile of porcine anterior pituitary cells isolated from gilts on days 15-16 of pregnancy.Scientific reports · 2026Article
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- The effect of visfatin on the transcriptomic profile of porcine anterior pituitary cells during periimplantation period.Scientific reports · 2025Article
- Physio-metabolic response, immune function, epigenetic markers, and reproductive performance of rabbits under environmental stress: the mitigating role of boswellia essential oil nanoemulsion.BMC veterinary research · 2025Article
- Determining the normal range of the dimensions and volume of the pituitary gland of children using a 3D magnetic resonance imaging (MRI) protocol in Imam Hossein Hospital of Isfahan in 2021 to 2024.American journal of neurodegenerative disease · 2025Article
- Contributions of white adipose tissue to energy requirements for female reproduction.Trends in endocrinology and metabolism: TEM · 2024Review
- The Impact of the Endocrine and Immunological Function of Adipose Tissue on Reproduction in Women with Obesity.International journal of molecular sciences · 2024Review
- Visfatin (NAMPT) affects global gene expression in porcine anterior pituitary cells during the mid-luteal phase of the oestrous cycle.Journal of animal science and biotechnology · 2024Article
- Status of visfatin in female reproductive function under normal and pathological conditions: a mini review.Molecular biology reports · 2024Review
- The Role of Adipokines in the Control of Pituitary Functions.Animals : an open access journal from MDPI · 2024Review
- The Effect of Visfatin on the Functioning of the Porcine Pituitary Gland: An In Vitro Study.Cells · 2023Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visfatin is a multifunctional protein which, besides the control of energy homeostasis, seems to be also involved in the regulation of female fertility through the influence on the endocrine hypothalamus-pituitary-gonadal axis, including the pituitary. The aim of this study was to investigate the expression of visfatin mRNA and protein in the anterior (AP) and posterior pituitary lobes of the pig during the oestrous cycle and early pregnancy. In AP, we also examined colocalisation of visfatin with pituitary tropic hormones. Moreover, we aimed to evaluate the in vitro effects of GnRH, FSH, LH, and insulin on visfatin protein concentration and secretion in AP cells during the cycle. The study showed that visfatin is present in all types of porcine pituitary endocrine cells and its expression is reliant on stage of the cycle or pregnancy. GnRH, FSH, LH and insulin stimulated visfatin secretion by AP cells on days 17 to 19 of the cycle, while on days 2 to 3 visfatin release was enhanced only by LH. Summarising, visfatin is locally produced in the pituitary in a way dependent on hormonal milieu typical for reproductive status of pigs. Further research is required to clarify the role of visfatin in the pituitary gland.
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