Evidence map›Paper›PMID 37880290›Full record

SynthesisNature communications2023

Systematic review and integrated data analysis reveal diverse pangolin-associated microbes with infection potential.

Run-Ze Ye, Xiao-Yang Wang, Yu-Yu Li, Bao-Yu Wang, Ke Song, Yi-Fei Wang, Jing Liu, Bai-Hui Wang, Shan-Shan Wang, Qing Xu and 11 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 2 countries.

Run-Ze Ye *Institute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.ORCID http://orcid.org/0000-0002-7239-5641
Xiao-Yang Wang *Institute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Yu-Yu Li *Institute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Bao-Yu Wang *Institute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Ke SongInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Yi-Fei WangInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Jing LiuInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Bai-Hui WangInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Shan-Shan WangInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Qing XuInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Ze-Hui LiInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Yi-Di DuInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Jin-Yue LiuInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Jia-Jing ZhengState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
Li-Feng DuInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China.
Wenqiang ShiState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.
Na JiaState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.ORCID http://orcid.org/0000-0003-0532-7064
Jia-Fu JiangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.ORCID http://orcid.org/0000-0002-4784-8813
Xiao-Ming CuiState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China. cuixm7@163.com.
Lin ZhaoInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China. zhaolin1989@sdu.edu.cn.
Wu-Chun CaoInstitute of EcoHealth, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P. R. China. caowuchun@126.com.ORCID http://orcid.org/0000-0002-5090-2251
Shandong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNInstitute of Microbiology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been increasing global concern about the spillover transmission of pangolin-associated microbes. To assess the risk of these microbes for emergence as human pathogens, we integrated data from multiple sources to describe the distribution and spectrum of microbes harbored by pangolins. Wild and trafficked pangolins have been mainly recorded in Asia and Africa, while captive pangolins have been reported in European and North American countries. A total of 128 microbes, including 92 viruses, 25 bacteria, eight protists, and three uncharacterized microbes, have been identified in five pangolin species. Out of 128 pangolin-associated microbes, 31 (including 13 viruses, 15 bacteria, and three protists) have been reported in humans, and 54 are animal-associated viruses. The phylogenetic analysis of human-associated viruses carried by pangolins reveals that they are genetically close to those naturally circulating among human populations in the world. Pangolins harbor diverse microbes, many of which have been previously reported in humans and animals. Abundant viruses initially detected in pangolins might exhibit risks for spillover transmission.

Indexed as

PangolinsAfricaAnimalsAsiaHumansNorth AmericaPhylogeny

Identifiers

PMID37880290
PMCPMC10600157
OpenAlexW4387950669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.