Small protein plays with big networks.

Valerie A Tornini

Abstract read

In one paragraph

Article in Trends in genetics : TIG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Valerie A TorniniDepartment of Genetics, Yale School of Medicine, New Haven, CT 06511, USA; Department of Integrative Biology and Physiology, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA; Institute for Society and Genetics, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. Electronic address: valerie.tornini@gmail.com.

Funding

Functional analysis of histone modifier Autism Spectrum Disorders risk genes in vertebrate developmentK99HD105001 · NICHD · YALE UNIVERSITY · PI TORNINI, VALERIE ANGELA · 2022 to 2023

$239k

NICHD NIH HHS K99 HD105001

6 · The paper itself

Abstract

Thousands of small proteins, called microproteins, are encoded in small open reading frames (smORFs) throughout the genome. Despite assumptions that these proteins would be too small to properly fold and function, a recent study by Chen et al. identifies the surprisingly complex roles of one such microprotein.

Indexed as

GenomeProteinsOpen Reading FramesProteins

Identifiers

PMID37879968

DOI10.1016/j.tig.2023.10.008

PMCPMC10847964

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.