Evidence map›Paper›PMID 37879711›Full record

ArticleBMJ case reports2023

Three-year remission of metastatic breast cancer with treatment with ado-trastuzumab emtansine.

Cecília Caramujo, Sara Nunes Reis, Ana Rita Garcia, Gabriela Sousa

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cecília CaramujoMedical Oncology, Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Porto, Portugal ce.caramujo@gmail.com.ORCID http://orcid.org/0000-0002-6707-7673
Sara Nunes ReisPathology, Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal.
Ana Rita GarciaMedical Oncology, Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Porto, Portugal.
Gabriela SousaMedical Oncology, Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Porto, Portugal.
Instituto Português de Oncologia de Coimbra Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, breast cancer is the most frequently diagnosed malignancy and the leading cause of oncological death in women. Metastatic disease at diagnosis (de novo stage IV breast cancer) will be identified in about 5% of patients. Treatment options vary based on several factors, namely whether the tumour is hormone receptor positive and whether human epidermal growth factor receptor 2 (HER2) is overexpressed. Here, we report a case of HER2 positive metastatic breast cancer on a woman in her late 30s, with remission for over 3 years under second-line treatment with ado-trastuzumab emtansine, with no significant toxicity and good tolerability. The timing to stop treatment under these circumstances presents a challenge and more data are needed to substantiate the decision to stop or maintain treatment in this small population.

Indexed as

Ado-Trastuzumab EmtansineAntineoplastic AgentsBreast NeoplasmsAdultErb-b2 Receptor Tyrosine KinasesFemaleHumansAdo-Trastuzumab EmtansineAntineoplastic AgentsErb-b2 Receptor Tyrosine KinasesBreast cancerOncology

Identifiers

PMID37879711
PMCPMC10603395
OpenAlexW4387948920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.