ArticleNature2023
TMPRSS2 is a functional receptor for human coronavirus HKU1.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
19.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 102 citations in OpenAlex.
- Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses.Nature microbiology · 2026Article
- Targeting virus-glycan recognition in influenza viruses and coronaviruses: from the molecular principles to glycomimetic antivirals strategies.RSC chemical biology · 2026Review
- Discovery of Highly Selective Noncovalent Macrocyclic Peptide Inhibitors Suppressing Both TMPRSS2 Protease Activity and Viral Receptor Function.Journal of medicinal chemistry · 2026Article
- Temperature-dependent replication and sensitivity to innate immunity of human coronavirus HKU1.Nature communications · 2026Article
- Lock out: targeting TMPRSS2 to block influenza and coronaviruses.Journal of virology · 2026Review
- Isolation and characterization of LH5, a novel rodent Embecovirus from Rattus tanezumi with respiratory tropism in a mouse model.BMC biology · 2026Article
- Concanavalin A targets phylogenetically conserved N-linked glycans on coronavirus spike proteins for broad-spectrum antiviral activity.Journal of virology · 2026Article
- OC43 clinical isolate spike proteins have distinct carbohydrate-binding properties.Nature communications · 2026Article
- Article
- Article
- TMPRSS2-mediated coronavirus spike activation and inhibition.Nature structural & molecular biology · 2026Article
- Establishment of a human coronavirus HKU1 infection evaluation system using apical-out airway organoids.The Journal of general virology · 2026Article
- Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Entry, replication and innate immunity evasion of BANAL-236, a SARS-CoV-2-related bat virus, in Rhinolophus and human cells.PLoS pathogens · 2026Article
- Monoclonal antibodies from COVID-19 convalescent patients target cryptic epitopes for broad SARS-CoV-2 neutralization.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Impact of cellular proteases on the function of antiviral antibodies.Journal of virology · 2026Review
- A Lung-Immune Dual-Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design.PLoS pathogens · 2026Article
- Chemoenzymatically Synthesized O-Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context.Angewandte Chemie (International ed. in English) · 2026Article
- MMP-9 regulates disulphide isomerase activity of TGM2 to enhance fusion glycoprotein-mediated syncytium formation of respiratory syncytial virus.Protein & cell · 2026Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 5 institutions in 2 countries.
Nell SaundersVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.ORCID 0000-0002-0872-1529
Ignacio FernandezStructural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Cyril PlanchaisHumoral Immunology Unit, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France.ORCID 0000-0002-5142-7253
Vincent MichelPathogenesis of Vascular Infections Unit, Institut Pasteur, INSERM, Paris, France.ORCID 0000-0002-7025-4343
Maaran Michael RajahVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Eduard Baquero SalazarNanoimaging core, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France.
Jeanne PostalVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Francoise PorrotVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.ORCID 0000-0001-8995-3614
Florence Guivel-BenhassineVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Catherine BlancPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris Cité, Paris, France.ORCID 0000-0003-4214-1381
Gaëlle Chauveau-Le FriecAntibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France.
Augustin MartinVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Ludivine GrzelakVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Rischa Maya OktaviaStructural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Annalisa MeolaStructural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Olivia AhouziStructural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Hunter Hoover-WatsonVirus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.
Matthieu ProtG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France.
Deborah DelauneG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France.ORCID 0000-0003-4970-9566
Marion CornelissenDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, Molecular Diagnostic Unit, University of Amsterdam, Amsterdam, The Netherlands.
Martin DeijsAmsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands.
Véronique MeriauxAntibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France.
Hugo MouquetHumoral Immunology Unit, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France.
Etienne Simon-LorièreG5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France.ORCID 0000-0001-8420-7743
Lia van der HoekAmsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands.ORCID 0000-0003-2803-642X
Pierre LafayeAntibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France.ORCID 0000-0002-5761-1342
Felix ReyStructural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.ORCID 0000-0002-9953-7988
Julian Buchrieser *Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France. julian.buchrieser@pasteur.fr.ORCID 0000-0003-4790-7577
Olivier Schwartz *Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France. olivier.schwartz@pasteur.fr.ORCID 0000-0002-0729-1475
Centre National de la Recherche Scientifique · FRInserm · FRInstitut Pasteur · FRAmsterdam Neuroscience · NLAmsterdam University Medical Centers · NL
Funding
Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaU01AI151758 · NIAID · INSTITUT PASTEUR · PI SAKUNTABHAI, ANAVAJ, SIMON-LORIERE, ETIENNE · 2020 to 2024
$6.7MNIAID NIH HHS U01 AI151758Wellcome Trust
Abstract
Four endemic seasonal human coronaviruses causing common colds circulate worldwide: HKU1, 229E, NL63 and OC43 (ref.
Indexed as
BetacoronavirusReceptors, VirusSerine EndopeptidasesSpike Glycoprotein, CoronavirusBronchiCommon ColdHumansMembrane FusionSARS-CoV-2Single-Domain AntibodiesSpecies SpecificityVirus InternalizationReceptors, VirusSerine EndopeptidasesSingle-Domain AntibodiesSpike Glycoprotein, CoronavirusTMPRSS2 protein, human
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.