Evidence map›Paper›PMID 37878802›Full record

ArticleRheumatology (Oxford, England)2024

The ATTRACT study: screening for the early identification of axial psoriatic arthritis in a cohort of Italian psoriatic patients.

Michele Maria Luchetti Gentiloni, Valentino Paci, Ilaria Cimaroli, Alice Agostinelli, Melania Giannoni, Anna Campanati, Federico Diotallevi, Marina Carotti, Francesco Sessa, Raffaella Sordillo and 15 more

Open access · hybridAbstract read
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In one paragraph

Article in Rheumatology (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 2 countries.

Michele Maria Luchetti GentiloniMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.ORCID 0000-0001-9132-7401
Valentino PaciMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Ilaria CimaroliMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Alice AgostinelliMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Melania GiannoniDermatology Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Anna CampanatiDermatology Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Federico DiotalleviDermatology Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Marina CarottiRadiology Clinic, Department of Radiological Sciences, Polytechnic University of Marche, Ancona, Italy.
Francesco SessaNeuroradiology Clinic, Department of Radiological Sciences, Polytechnic University of Marche, Ancona, Italy.
Raffaella SordilloMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Cristina MacchiniMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Federico FioriniMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Leonardo MassaccesiMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Monia CiferriMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Marco GigliMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Valentina MarconiMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Lucia PeriniMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Andrea MaraniDermatology Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Andrea GiovagnoniRadiology Clinic, Department of Radiological Sciences, Polytechnic University of Marche, Ancona, Italy.
Gabriele PolonaraNeuroradiology Clinic, Department of Radiological Sciences, Polytechnic University of Marche, Ancona, Italy.
Anna Maria OffidaniDermatology Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Devis BenfaremoMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Fabian ProftDepartment of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité-Universitätsmedizin, Berlin, Germany.ORCID 0000-0003-4306-033X
Denis PoddubnyyDepartment of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité-Universitätsmedizin, Berlin, Germany.ORCID 0000-0002-4537-6015
Gianluca MoronciniMedical Clinic, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Marche Polytechnic University · ITCharité - Universitätsmedizin Berlin · DE

Funding

AbbVie Srl
6 · The paper itself

Abstract

objectiveThere is growing interest in the early identification of patients with axial PsA (axPsA). We aimed to evaluate whether a dermatology-based screening strategy could help to identify axPsA patients.

methodsThe dermatologist-centred screening (DCS) questionnaire was administrated by dermatologists to consecutive patients fulfilling the inclusion criteria [(i) age ≥18 years and (ii) clinical diagnosis of psoriasis made by a dermatologist] to identify patients eligible (affirmative answers 1-3c of the DCS) for rheumatological evaluation. Clinical, laboratory, genetic and imaging data were collected from all referred patients.

resultsAmong the 365 patients screened, 265 fulfilled the inclusion criteria and 124/265 (46.8%) were eligible for rheumatological referral. Diagnosis of axPsA, with or without peripheral PsA (pPsA), was made in 36/124 (29.0%) patients; pPsA without axial involvement was found in 21/124 (16.9%) patients. Back pain at screening was recorded in 174 (66%) patients, with 158 (60%) reporting a back pain duration longer than 3 months and 140 (53%) reporting back pain onset before the age of 45 years. Active inflammatory and/or structural post-inflammatory changes in the sacroiliac joints and/or spine were observed in all axPsA patients. Patients with PsA showed a numerically longer duration of back pain and higher CRP levels in comparison with patients with psoriasis without PsA.

conclusionThe DCS tool proved to be a valuable screening strategy for detecting and characterizing patients with axPsA in a real-life cohort of psoriasis patients in a dermatological setting and helped to identify a substantial number of patients affected by undiagnosed pPsA.

Indexed as

Arthritis, PsoriaticEarly DiagnosisAdultAgedAxial SpondyloarthritisBack PainCohort StudiesFemaleHumansItalyMaleMass ScreeningMiddle AgedPsoriasisSurveys and Questionnairesaxialclinical characterizationdermatologistearly diagnosispsoriatic arthritisscreening

Identifiers

PMID37878802
PMCPMC11292137
OpenAlexW4387948701

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.