SynthesisChemical senses2023
Olfaction and declarative memory in aging: a meta-analysis.
Synthesis in Chemical senses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population-Based Rhineland Study.International forum of allergy & rhinology · 2026Article
- Alzheimer's disease and cerebrovascular biomarkers in relation to odor identification in a naturalistic clinical cohort.Alzheimer's research & therapy · 2026Article
- Olfactory decline in aging: longitudinal trajectories and associations with cognitive decline and postmortem neuropathology.medRxiv : the preprint server for health sciences · 2026Article
- Olfactory enrichment mitigates delayed neurocognitive recovery after major orthopaedic surgery in older patients: A randomised controlled trial.General psychiatry · 2026Article
- The predictive role of olfactory identification on episodic memory and mild cognitive impairment: Results from the CIMA-Q cohort.Journal of Alzheimer's disease : JAD · 2026Article
- Olfactory dysfunction increases progression to dementia in cognitively impaired older adults: a 12-year population-based study.GeroScience · 2026Article
- Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction.International forum of allergy & rhinology · 2025Article
- Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction.International forum of allergy & rhinology · 2025Article
- Resting-state hippocampal asymmetry as a marker for memory and olfactory deficit in parkinson's disease.Scientific reports · 2025Article
- The AROMHA brain health test is a remote olfactory assessment to screen for cognitive impairment.Scientific reports · 2025Article
- Impaired odor recognition memory in Parkinson's disease linked to absent functional hippocampal asymmetry.NPJ Parkinson's disease · 2025Article
- Free odor identification engages domain-general cognitive abilities in old adults.Chemical senses · 2025Article
- Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults.Frontiers in aging neuroscience · 2025Article
- Better olfaction was associated with lower healthcare expenditure among physically independent Japanese community-dwelling older adults: the Yanai study.Frontiers in aging · 2025Article
- Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment.European journal of investigation in health, psychology and education · 2024Article
- Factors influencing olfactory function in an adult general population sample: the CHRIS study.Chemical senses · 2024Article
- Lower odor identification in subjective cognitive decline: a meta-analysis.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Olfactory Testing With Focus on Odor Identification for Early Detection of Alzheimer's Disease in Mild Cognitive Impairment.American journal of Alzheimer's disease and other dementiasReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Olfactory and declarative memory performances are associated, as both functions are processed by overlapping medial-temporal and prefrontal structures and decline in older adults. While a decline in olfactory identification may be related to a decline in declarative memory, the relationship between olfactory detection threshold and declarative memory remains unclear. In this meta-analysis, we assessed (i) the relationship between olfactory identification/detection threshold and verbal declarative memory in cognitively normal older adults, and (ii) the effect of age on these relationships. We included articles from PsychNet, PubMed, and Academic Search Complete according to the following criteria: (i) inclusion of cognitively normal older adults; (ii) assessment of episodic or semantic memory; and (iii) assessment of olfactory identification or detection threshold. Seventeen studies and 22 effect sizes were eligible and included in this meta-analysis. Olfactory identification was associated with episodic (small effect size: r = 0.19; k = 22) and semantic memory (small effect size: r = 0.16; k = 23). Similarly, the olfactory detection threshold was associated with both episodic (small to medium effect size: r = 0.25; k = 5) and semantic memory (small effect size: r = 0.17; k = 7). Age was found to moderate the relationship between olfactory detection threshold and memory performance. Both olfactory identification and detection threshold performances are associated with declarative memory in older adults, and age only moderates the relationship between olfactory detection threshold and declarative memory performances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.