Evidence map›Paper›PMID 37878751›Full record

ArticleExperimental physiology2023

Naturally menstruating women exhibit lower cardiovagal baroreflex sensitivity than oral contraceptive users during the lower hormone phase.

Sara E Mascone, Dain W Jacob, Lauren E Eagan, Jennifer L Harper, Jacqueline K Limberg, Sushant M Ranadive

Open access · diamondAbstract read
In one paragraph

Article in Experimental physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sara E MasconeDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.ORCID 0000-0002-2845-4544
Dain W JacobDepartment of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, USA.
Lauren E EaganDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.ORCID 0000-0003-4746-7540
Jennifer L HarperDepartment of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, USA.
Jacqueline K LimbergDepartment of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, USA.ORCID 0000-0001-9982-5851
Sushant M RanadiveDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.ORCID 0000-0003-1674-4285
University of Maryland, College Park · USUniversity of Missouri · US

Funding

Sex disparities in hypoxic sympatholysis and impact of obesityR01HL153523 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI LIMBERG, JACQUELINE K · 2020 to 2024
$2.7M
Reflex responses to intermittent hypoxia in humans: Mechanisms and consequencesR00HL130339 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI LIMBERG, JACQUELINE K · 2017 to 2019
$729k
Reflex responses to intermittent hypoxia in humans: Mechanisms and consequencesK99HL130339 · NHLBI · MAYO CLINIC ROCHESTER · PI LIMBERG, JACQUELINE K · 2016 to 2017
$156k
American Heart Association-American Stroke Association 909014NHLBI NIH HHS K99 HL130339NHLBI NIH HHS R00 HL130339NHLBI NIH HHS R01 HL153523
6 · The paper itself

Abstract

The present study evaluated cardiovagal baroreflex sensitivity (BRS) across the menstrual/pill cycle in naturally menstruating women (NAT women) and women using oral hormonal contraceptives (OCP women). In 21 NAT women (23 ± 4 years old) and 22 OCP women (23 ± 3 years old), cardiovagal BRS and circulating concentrations of estradiol and progesterone were evaluated during the lower hormone (early follicular/placebo pill) and higher hormone (late follicular to early luteal/active pill) phases. During the lower hormone phase, cardiovagal BRS up, down and mean gain were lower in NAT women (15.6 ± 8.3, 15.2 ± 6.1 and 15.1 ± 7.1 ms/mmHg) compared with OCP women (24.7 ± 9.4, 22.9 ± 8.0 and 23.0 ± 8.0 ms/mmHg) (P = 0.003, P = 0.002 and P = 0.003, respectively), and higher oestrogen (R

Indexed as

MenstruationProgesteroneAdultBaroreflexContraceptives, OralEstradiolEstrogensFemaleHumansYoung AdultContraceptives, OralEstradiolEstrogensProgesteronebaroreflex sensitivityblood pressure regulationsex hormones

Identifiers

PMID37878751
PMCPMC10843041
OpenAlexW4387948831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.