SynthesisPediatric blood & cancer2024
Physical capacity in children and adolescents with newly diagnosed cancer: A systematic review and meta-analysis.
Synthesis in Pediatric blood & cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Cardiorespiratory fitness and health in children and adolescents: an overview of systematic reviews with meta-analyses representing over 125 000 observations covering 33 health-related outcomes.British journal of sports medicine · 2025Pooled it
- Parents' perceptions of physical activity for their children with cancer: a qualitative meta-synthesis.Frontiers in pediatrics · 2025Pooled it
- Gross motor function, functional level, physical performance, and muscle strength in preschool children newly diagnosed with cancer: Data from the RePlay trial.European journal of pediatrics · 2026Trial
- Childhood cancer and future cardiometabolic health.npj metabolic health and disease · 2026Review
- Article
- Muscle fitness and physical function in children and adolescents with newly diagnosed cancer.Frontiers in pediatrics · 2026Article
- Tumor Signatures of Physical Fitness: Insights from a Preclinical Model.Medicine and science in sports and exercise · 2026Article
- Social and physical activity as rehabilitation for preschool kids with cancer-study protocol for a randomized controlled trial.Frontiers in pediatrics · 2026Article
- Exercise-induced symptoms in young childhood cancer survivors.Journal of cancer survivorship : research and practice · 2025Article
- Establishing consensus on defining the physically vulnerable child with cancer: a protocol for an international Delphi approach.BMJ paediatrics open · 2025Article
- Muscle strength, functional mobility, and performance in activities of daily living in children and adolescents with cancer.European journal of pediatrics · 2024Observational
- Severely reduced physical performance is already present at the time of admission for stem cell transplantation.BMJ open sport & exercise medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo review the body of evidence on cardiorespiratory fitness, muscle strength, and physical performance in children with newly diagnosed cancer, five databases (MEDLINE, Embase, CINAHL, CENTRAL, and Web of Science) were searched on December 19, 2022.
methodsThirteen studies, embodying 594 participants within 1 month of cancer diagnosis and 3674 healthy controls were included. Eighteen different outcomes on cardiorespiratory fitness (n = 2), muscle strength (n = 5), physical performance (n = 10), and adverse events (n = 1) were analyzed.
resultsFifteen out of 17 outcomes on physical capacity showed severe impairments compared with healthy controls. Where possible, random-effects meta-analysis was conducted to synthesize the results. No adverse events were reported related to testing.
conclusionChildren with cancer have impaired cardiorespiratory fitness, muscle strength, and physical performance within the first month after diagnosis. However, the evidence is based on a small number of studies with large clinical heterogeneity, limiting the certainty of evidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.