Evidence map›Paper›PMID 37877735›Full record

ArticlemBio2023

The protein phosphatase PPKL is a key regulator of daughter parasite development in

Chunlin Yang, Emma H Doud, Emily Sampson, Gustavo Arrizabalaga

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Proteomics Applications inPathogens (Basel, Switzerland) · 2023
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chunlin YangDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0001-5187-8436
Emma H DoudDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Emily SampsonDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Gustavo ArrizabalagaDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-4445-0375
Indiana University School of MedicineIndiana University Health · US

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Sara K Quinney · 1999 to 2026
$59.3M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Interleukin-1 and Steroid Signaling Drive Toxoplasma-induced Prostatic HyperplasiaR01DK124067 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A, JERDE, TRAVIS J · 2020 to 2023
$2.1M
Regulation of mitochondrial morphodynamics in Toxoplasma gondiiR01AI149766 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI ARRIZABALAGA, GUSTAVO A · 2020 to 2024
$2.0M
Homologs of brassinosteroid signaling proteins in Toxoplasma gondii regulate parasite divisionR21AI164619 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A · 2021 to 2022
$436k
HHS | National Institutes of Health (NIH) R01AI149766HHS | National Institutes of Health (NIH) R01DK124067HHS | National Institutes of Health (NIH) R21AI164619NCATS NIH HHS UL1 TR002529NCI NIH HHS P30 CA082709NIAID NIH HHS R01 AI149766NIAID NIH HHS R21 AI164619NIDDK NIH HHS R01 DK124067
6 · The paper itself

Abstract

importance

Indexed as

Phosphoprotein PhosphatasesProtozoan ProteinsToxoplasmaAnimalsHumansToxoplasmosisPhosphoprotein PhosphatasesProtozoan Proteinscell cycleCrk1divisionDYRK1phosphatasephosphorylationPPKLSPM1Toxoplasma

Identifiers

PMID37877735
PMCPMC10746186
OpenAlexW4387931905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.