Evidence map›Paper›PMID 37877724›Full record

Observational studyNeurorehabilitation and neural repair2023

Mild Stroke, Serious Problems: Limitations in Balance and Gait Capacity and the Impact on Fall Rate, and Physical Activity.

Jolanda M B Roelofs, Sarah B Zandvliet, Ingrid M Schut, Anouk C M Huisinga, Alfred C Schouten, Henk T Hendricks, Digna de Kam, Leo A M Aerden, Johannes B J Bussmann, Alexander C H Geurts and 1 more

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in Neurorehabilitation and neural repair, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07428824 (Effects of Functional Action Observation Therapy With Rhythmic Auditory Cueing on Balance and Gait in Patients With Stroke), which is not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07428824 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Functional Action Observation Therapy With Rhythmic Auditory Cueing on Balance and Gait in Patients With Stroke

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2026Enrolled40ConditionsStrokeArmsFunctional Action Observation Therapy, Functional Action Observation Therapy with rhythmic auditory stimulation group
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  9. Altered walking gaze behavior after stroke: more than meets the eye.Journal of neuroengineering and rehabilitation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Jolanda M B RoelofsDepartment of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Sarah B ZandvlietDepartment of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-1950-0510
Ingrid M SchutDepartment of Biomechanical Engineering, Delft University of Technology, Delft, The Netherlands.
Anouk C M HuisingaRehabilitation Centre Klimmendaal, Arnhem, The Netherlands.
Alfred C SchoutenDepartment of Biomechanical Engineering, Delft University of Technology, Delft, The Netherlands.
Henk T HendricksDepartment of Rehabilitation Medicine, Rijnstate Hospital Arnhem, Arnhem, The Netherlands.
Digna de KamDepartment of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Leo A M AerdenDepartment of Neurology, Reinier de Graafgasthuis, Delft, The Netherlands.
Johannes B J BussmannDepartment of Rehabilitation Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0002-7496-5636
Alexander C H GeurtsDepartment of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Vivian WeerdesteynDepartment of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLDelft University of Technology · NLErasmus MC · NLReinier de Graaf Hospital · NLRijnstate Hospital · NLUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels.

methodsAn observational case-control study was performed. Main outcomes included the Mini-Balance Evaluation Systems Test (mini-BEST), Timed Up and Go (TUG), 10-m Walking Test (10-MWT), and 6-item version Activity-specific Balance Confidence (6-ABC) scale which were measured in 1 session. Objectively measured daily physical activity was measured for 7 consecutive days. Fall rate in daily life was recorded for 12 months. Individuals after a mild stroke were considered eligible when they: (1) sustained a transient ischemic attack or stroke longer than 6 months ago, resulting in motor and/or sensory loss in the contralesional leg at the time of stroke, (2) showed (near-) complete motor function, that is, ≥24 points on the Fugl-Meyer Assessment-Lower Extremity (range: 0-28).

resultsForty-seven healthy controls and 70 participants after mild stroke were included. Participants with stroke fell more than twice as often as healthy controls, had a 2 point lower median score on the mini-BEST, were 1.7 second slower on TUG, 0.6 km/h slower on the 10-MWT, and had a 12% lower 6-ABC score. Intensity for both total activity (8%) as well as walking activity (6%) was lower in the participants with stroke, while no differences were found in terms of duration.

conclusionsIndividuals in the chronic phase after a mild stroke demonstrate persistent balance limitations and have an increased fall risk. Our results point at an unmet clinical need in this population.

Indexed as

StrokeStroke RehabilitationCase-Control StudiesFearGaitHumansPostural BalanceWalkingaccidental fallsgaitpostural balancestrokestroke rehabilitationtransient ischemic attack

Identifiers

PMID37877724
PMCPMC10685695
OpenAlexW4387931264

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.