Evidence map›Paper›PMID 37877698›Full record

ArticlemBio2023

Characterizing the microbiome of patients with myeloproliferative neoplasms during a Mediterranean diet intervention.

Julio Avelar-Barragan, Laura F Mendez Luque, Jenny Nguyen, Hellen Nguyen, Andrew O Odegaard, Angela G Fleischman, Katrine L Whiteson

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Julio Avelar-Barragan *Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California, USA.ORCID 0000-0003-4710-7182
Laura F Mendez Luque *Department of Biological Chemistry, University of California Irvine, Irvine, California, USA.
Jenny NguyenDivision of Hematology/Oncology, University of California Irvine, Irvine, California, USA.
Hellen NguyenDivision of Hematology/Oncology, University of California Irvine, Irvine, California, USA.
Andrew O OdegaardDepartment of Epidemiology and Biostatistics, University of California Irvine, Irvine, California, USA.
Angela G FleischmanDepartment of Biological Chemistry, University of California Irvine, Irvine, California, USA.ORCID 0000-0002-3701-6079
Katrine L WhitesonDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California, USA.ORCID 0000-0002-5423-6014
University of California, Irvine · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
MINORITY BIOMEDICAL RESEARCHERS PROGRAMR25GM055246 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI MOTA-BRAVO, LUIS M · 1996 to 2022
$15.3M
NCI NIH HHS P30 CA062203NIGMS NIH HHS R25 GM055246
6 · The paper itself

Abstract

importanceThe gut microbiome serves as an interface between the host and the diet. Diet and the gut microbiome both play important roles in managing inflammation, which is a key aspect of myeloproliferative neoplasm (MPN). Studies have shown that a Mediterranean (MED) diet can reduce inflammation. Therefore, we longitudinally characterized the gut microbiomes of MPN patients in response to Mediterranean or standard 2020 US Guidelines for Americans dietary counseling to determine whether there were microbiome-associated changes in inflammation. We did not find significant changes in the gut microbiome associated with diet, but we did find several associations with inflammation. This research paves the way for future studies by identifying potential mechanistic targets implicated in inflammation within the MPN gut microbiome.

Indexed as

Diet, MediterraneanGastrointestinal MicrobiomeMyeloproliferative DisordersAdultAgedBacteriaFemaleHumansInflammationLongitudinal StudiesMaleMiddle Ageddietgut microbiomeMediterraneanmyeloproliferativeneoplasm

Identifiers

PMID37877698
PMCPMC10746218
OpenAlexW4387931715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.