Evidence map›Paper›PMID 37877696›Full record

ArticleNanomedicine (London, England)2023

Characterization and quantification of adeno-associated virus capsid-loading states by multi-wavelength analytical ultracentrifugation with UltraScan.

Amy Henrickson, Xiaozhe Ding, Austin G Seal, Zhe Qu, Lauren Tomlinson, John Forsey, Viviana Gradinaru, Kazuhiro Oka, Borries Demeler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomedicine (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amy HenricksonDepartment of Chemistry & Biochemistry, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada.ORCID 0000-0003-3266-5202
Xiaozhe DingDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-0267-0791
Austin G SealGene Vector Core, Advanced Technology Cores, Baylor College of Medicine Houston, TX 77030, USA.
Zhe QuDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Lauren TomlinsonPharmaron Biologics Ltd, Speke, Liverpool, L24 8RB, UK.
John ForseyPharmaron Biologics Ltd, Speke, Liverpool, L24 8RB, UK.ORCID 0009-0001-5557-4381
Viviana GradinaruDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-5868-348X
Kazuhiro OkaGene Vector Core, Advanced Technology Cores, Baylor College of Medicine Houston, TX 77030, USA.ORCID 0000-0003-2159-3637
Borries DemelerDepartment of Chemistry & Biochemistry, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada.ORCID 0000-0002-2414-9518

Funding

Engineered AAV Identification, Validation, and Dissemination Pipeline for Brain Cell Type-Specific Manipulation Across SpeciesUF1MH128336 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI FOX, ANDREW S, GRADINARU, VIVIANA · 2021 to 2021
$6.1M
Development of an UltraScan Meta-Scheduler for HPC Job SubmissionR01GM120600 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Emre H. Brookes, BORRIES DEMELER · 2016 to 2026
$3.6M
NIGMS NIH HHS R01 GM120600NIMH NIH HHS UF1 MH128336
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CapsidDependovirusGenetic VectorsMicroscopy, Electron, TransmissionUltracentrifugationadeno-associated virusanalytical buoyant density gradient equilibriumgene therapymulti-wavelength analytical ultracentrifugationsedimentation velocityUltraScanviral capsid quantificationviral vector

Identifiers

PMID37877696
PMCPMC10652292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.