ArticleMicrobiologyOpen2023
Transcriptomics-guided identification of an algicidal protease of the marine bacterium Kordia algicida OT-1.
Article in MicrobiologyOpen, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 11 citations in OpenAlex.
- Marine BacteriumJournal of natural products · 2026Article
- Induced pathogenicity toward open-ocean diatoms by a filterable bacterium Ekhidna algicida sp. nov.The ISME journal · 2026Article
- Rapid adaptive evolution of oxylipin-based chemical defense against algicidal bacteria in a bloom-forming diatom.The ISME journal · 2026Article
- A bloom of a single bacterium shapes the microbiome during outdoor diatom cultivation collapse.mSystems · 2025Article
- Friends and foes: symbiotic and algicidal bacterial influence onISME communications · 2025Article
- Article
- Transcriptomics-guided identification of an algicidal protease of the marine bacterium Kordia algicida OT-1.MicrobiologyOpen · 2023Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
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Abstract
In recent years, interest in algicidal bacteria has risen due to their ecological importance and their potential as biotic regulators of harmful algal blooms. Algicidal bacteria shape the plankton communities of the oceans by inhibiting or lysing microalgae and by consuming the released nutrients. Kordia algicida strain OT-1 is a model marine algicidal bacterium that was isolated from a bloom of the diatom Skeletonema costatum. Previous work has suggested that algicidal activity is mediated by secreted proteases. Here, we utilize a transcriptomics-guided approach to identify the serine protease gene KAOT1_RS09515, hereby named alpA1 as a key element in the algicidal activity of K. algicida. The protease AlpA1 was expressed and purified from a heterologous host and used in in vitro bioassays to validate its activity. We also show that K. algicida is the only algicidal species within a group of four members of the Kordia genus. The identification of this algicidal protease opens the possibility of real-time monitoring of the ecological impact of algicidal bacteria in natural phytoplankton blooms.
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